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10.1371/journal.pone.0180256

http://scihub22266oqcxt.onion/10.1371/journal.pone.0180256
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suck abstract from ncbi


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pmid28678811
      PLoS+One 2017 ; 12 (7 ): e0180256
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  • Preliminary fast diagnosis of severe fever with thrombocytopenia syndrome with clinical and epidemiological parameters #MMPMID28678811
  • Hu J ; Li Z ; Hong L ; Bao C ; Zhang Z ; Zhang H ; He H ; Wang X ; Liu W ; Peng Z ; Shi L ; Zhu F
  • PLoS One 2017[]; 12 (7 ): e0180256 PMID28678811 show ga
  • OBJECTIVES: To identify specific clinical and epidemiological parameters for clinical diagnosis of SFTSV infection with relatively higher accuracy. METHODS: 231 suspected cases of SFTS were reported by various medical institutions from 2011 to 2013 in Jiangsu Province, China. They were followed with SFTSV diagnosis tests and interview-administered questionnaires about demographic characteristics, clinical symptoms and epidemiological exposure factors. Univariate and multivariable logistic regression analysis were used to examine the diagnostic value of these parameters. RESULTS: SFTSV infection occurred only from April to October annually and usually in hilly areas of specific regions. Three prediction models of SFTSV infection were constructed. Model 3 with clinical and epidemiological parameters combined the benefits of both Model 1and Model 2, which was optimal and had an overall accuracy of 80.2%. Independent indicators for clinical diagnosis of SFTSV infection in Model 3 were as follows: lymphadenopathy (P = 0.01), leucopenia (P<0.01), age >50 years (P = 0.01), tick bites (P<0.01), raising domestic animals in the residential areas (P<0.01) and farming (P = 0.03). CONCLUSIONS: Our results show that using a combination of clinical and epidemiological parameters may be a feasible strategy to provide preliminary fast diagnosis as differentiating SFTSV infection from SFTS-like diseases, thus reducing the risk of misdiagnosis.
  • |Adolescent [MESH]
  • |Adult [MESH]
  • |Aged [MESH]
  • |Aged, 80 and over [MESH]
  • |Agriculture [MESH]
  • |Animals [MESH]
  • |Bunyaviridae Infections/*diagnosis/epidemiology/virology [MESH]
  • |Bunyaviridae/physiology [MESH]
  • |China/epidemiology [MESH]
  • |Feasibility Studies [MESH]
  • |Female [MESH]
  • |Geography [MESH]
  • |Host-Pathogen Interactions [MESH]
  • |Humans [MESH]
  • |Logistic Models [MESH]
  • |Male [MESH]
  • |Mass Screening/*methods [MESH]
  • |Middle Aged [MESH]
  • |Multivariate Analysis [MESH]
  • |Phlebotomus Fever/*diagnosis/epidemiology/virology [MESH]
  • |Surveys and Questionnaires [MESH]
  • |Syndrome [MESH]
  • |Thrombocytopenia/*diagnosis/epidemiology/virology [MESH]
  • |Tick Bites [MESH]


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  • suck abstract from ncbi

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