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10.1042/BST20160329 http://scihub22266oqcxt.onion/10.1042/BST20160329 C5497583!5497583!28408477     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28408477&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biochem+Soc+Trans 2017 ; 45 (2): 371-9 Nephropedia Template TP {{tp|p=28408477|t=2017. Pseudoscaffolds and anchoring proteins: the difference is in the details |pdf=|usr=}}{{28408477}} gab.com Text Pseudoscaffolds and anchoring proteins: the difference is in the details JO: Biochem Soc Trans http://www.kidney.de/pget.php?&tw=1&pmid=28408477 #FOAvip Pseudokinases and pseudophosphatases possess the ability to bind substrates without catalyzing their modification, thereby providing a mechanism to recruit potential phosphotargets away from active enzymes. Since many of these pseudoenzymes possess other characteristics such as localization signals, separate catalytic sites, and protein?protein interaction domains, they have the capacity to influence signaling dynamics in local environments. In a similar manner, the targeting of signaling enzymes to subcellular locations by A-kinase-anchoring proteins (AKAPs) allows for precise and local control of second messenger signaling events. Here, we will discuss how pseudoenzymes form ?pseudoscaffolds? and compare and contrast this compartment-specific regulatory role with the signal organization properties of AKAPs. The mitochondria will be the focus of this review, as they are dynamic organelles that influence a broad range of cellular processes such as metabolism, ATP synthesis, and apoptosis. Twit Text FOAVip Pseudoscaffolds and anchoring proteins: the difference is in the details ????Biochem Soc Trans http://www.kidney.de/pget.php?&tw=1&pmid=28408477 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28408477 #FOAvip English Wikipedia <ref>{{Cite pmid|28408477}}</ref> Pseudoscaffolds and anchoring proteins: the difference is in the details #MMPMID28408477 Aggarwal-Howarth S; Scott JD Biochem Soc Trans 2017[Apr]; 45 (2): 371-9 PMID28408477show ga Pseudokinases and pseudophosphatases possess the ability to bind substrates without catalyzing their modification, thereby providing a mechanism to recruit potential phosphotargets away from active enzymes. Since many of these pseudoenzymes possess other characteristics such as localization signals, separate catalytic sites, and protein?protein interaction domains, they have the capacity to influence signaling dynamics in local environments. In a similar manner, the targeting of signaling enzymes to subcellular locations by A-kinase-anchoring proteins (AKAPs) allows for precise and local control of second messenger signaling events. Here, we will discuss how pseudoenzymes form ?pseudoscaffolds? and compare and contrast this compartment-specific regulatory role with the signal organization properties of AKAPs. The mitochondria will be the focus of this review, as they are dynamic organelles that influence a broad range of cellular processes such as metabolism, ATP synthesis, and apoptosis. äPseudoscaffolds and anchoring proteins: the difference is in the detai(epmc).pdf DeepDyve Pubget Overpricing