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10.1212/WNL.0000000000004058 http://scihub22266oqcxt.onion/10.1212/WNL.0000000000004058 C5496518!5496518 !28592453     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28592453 &cmd=llinks): Failed to open stream: HTTP request failed! 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Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium |pdf=|usr=}}{{28592453 }} gab.com Text Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium JO: Neurology http://www.kidney.de/pget.php?&tw=1&pmid=28592453 #FOAvip The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous report, which has been in widespread use for the last decade. The revised DLB consensus criteria now distinguish clearly between clinical features and diagnostic biomarkers, and give guidance about optimal methods to establish and interpret these. Substantial new information has been incorporated about previously reported aspects of DLB, with increased diagnostic weighting given to REM sleep behavior disorder and (123)iodine-metaiodobenzylguanidine (MIBG) myocardial scintigraphy. The diagnostic role of other neuroimaging, electrophysiologic, and laboratory investigations is also described. Minor modifications to pathologic methods and criteria are recommended to take account of Alzheimer disease neuropathologic change, to add previously omitted Lewy-related pathology categories, and to include assessments for substantia nigra neuronal loss. Recommendations about clinical management are largely based upon expert opinion since randomized controlled trials in DLB are few. Substantial progress has been made since the previous report in the detection and recognition of DLB as a common and important clinical disorder. During that period it has been incorporated into DSM-5, as major neurocognitive disorder with Lewy bodies. There remains a pressing need to understand the underlying neurobiology and pathophysiology of DLB, to develop and deliver clinical trials with both symptomatic and disease-modifying agents, and to help patients and carers worldwide to inform themselves about the disease, its prognosis, best available treatments, ongoing research, and how to get adequate support. Twit Text FOAVip Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium ????Neurology http://www.kidney.de/pget.php?&tw=1&pmid=28592453 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28592453 #FOAvip English Wikipedia <ref>{{Cite pmid|28592453 }}</ref> Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium #MMPMID28592453 McKeith IG ; Boeve BF ; Dickson DW ; Halliday G ; Taylor JP ; Weintraub D ; Aarsland D ; Galvin J ; Attems J ; Ballard CG ; Bayston A ; Beach TG ; Blanc F ; Bohnen N ; Bonanni L ; Bras J ; Brundin P ; Burn D ; Chen-Plotkin A ; Duda JE ; El-Agnaf O ; Feldman H ; Ferman TJ ; Ffytche D ; Fujishiro H ; Galasko D ; Goldman JG ; Gomperts SN ; Graff-Radford NR ; Honig LS ; Iranzo A ; Kantarci K ; Kaufer D ; Kukull W ; Lee VMY ; Leverenz JB ; Lewis S ; Lippa C ; Lunde A ; Masellis M ; Masliah E ; McLean P ; Mollenhauer B ; Montine TJ ; Moreno E ; Mori E ; Murray M ; O'Brien JT ; Orimo S ; Postuma RB ; Ramaswamy S ; Ross OA ; Salmon DP ; Singleton A ; Taylor A ; Thomas A ; Tiraboschi P ; Toledo JB ; Trojanowski JQ ; Tsuang D ; Walker Z ; Yamada M ; Kosaka K Neurology 2017[Jul]; 89 (1 ): 88-100 PMID28592453 show ga The Dementia with Lewy Bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous report, which has been in widespread use for the last decade. The revised DLB consensus criteria now distinguish clearly between clinical features and diagnostic biomarkers, and give guidance about optimal methods to establish and interpret these. Substantial new information has been incorporated about previously reported aspects of DLB, with increased diagnostic weighting given to REM sleep behavior disorder and (123)iodine-metaiodobenzylguanidine (MIBG) myocardial scintigraphy. The diagnostic role of other neuroimaging, electrophysiologic, and laboratory investigations is also described. Minor modifications to pathologic methods and criteria are recommended to take account of Alzheimer disease neuropathologic change, to add previously omitted Lewy-related pathology categories, and to include assessments for substantia nigra neuronal loss. Recommendations about clinical management are largely based upon expert opinion since randomized controlled trials in DLB are few. Substantial progress has been made since the previous report in the detection and recognition of DLB as a common and important clinical disorder. During that period it has been incorporated into DSM-5, as major neurocognitive disorder with Lewy bodies. There remains a pressing need to understand the underlying neurobiology and pathophysiology of DLB, to develop and deliver clinical trials with both symptomatic and disease-modifying agents, and to help patients and carers worldwide to inform themselves about the disease, its prognosis, best available treatments, ongoing research, and how to get adequate support. |*Biomarkers [MESH] |*Practice Guidelines as Topic [MESH] |Humans [MESH]Diagnosis and management of dementia with Lewy bodies: Fourth consensu(epmc).pdf DeepDyve Pubget Overpricing