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10.1016/j.omtn.2017.06.005 http://scihub22266oqcxt.onion/10.1016/j.omtn.2017.06.005 C5496203/?report=reader!5496203!28918016     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mol+Ther+Nucleic+Acids 2017 ; 8 (ä): 132-43 Nephropedia Template TP {{tp|p=28918016|t=2017. Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine |pdf=|usr=}}{{28918016}} gab.com Text Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine JO: Mol Ther Nucleic Acids http://www.kidney.de/pget.php?&tw=1&pmid=28918016 #FOAvip In the past few years, therapeutic microRNA (miRNA) and small interfering RNA (siRNA) are some of the most important biopharmaceuticals that are in commercial space as future medicines. This review summarizes the patents of miRNA- and siRNA-based new drugs, and also provides a snapshot about significant biopharmaceutical companies that are investing for the therapeutic development of miRNA and siRNA molecules. An insightful view about individual siRNA and miRNA drugs has been depicted with their present status, which is gaining attention in the therapeutic landscape. The efforts of the biopharmaceuticals are discussed with the status of their preclinical and/or clinical trials. Here, some of the setbacks have been highlighted during the biopharmaceutical development of miRNA and siRNA as individual therapeutics. Finally, a snapshot is illustrated about pharmacokinetics, pharmacodynamics with absorption, distribution, metabolism, and excretion (ADME), which is the fundamental development process of these therapeutics, as well as the delivery system for miRNA- and siRNA-based drugs. Twit Text FOAVip Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine ????Mol Ther Nucleic Acids http://www.kidney.de/pget.php?&tw=1&pmid=28918016 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28918016 #FOAvip English Wikipedia <ref>{{Cite pmid|28918016}}</ref> Therapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Generation Medicine #MMPMID28918016 Chakraborty C; Sharma AR; Sharma G; Doss CGP; Lee SS Mol Ther Nucleic Acids 2017[Sep]; 8 (ä): 132-43 PMID28918016show ga In the past few years, therapeutic microRNA (miRNA) and small interfering RNA (siRNA) are some of the most important biopharmaceuticals that are in commercial space as future medicines. This review summarizes the patents of miRNA- and siRNA-based new drugs, and also provides a snapshot about significant biopharmaceutical companies that are investing for the therapeutic development of miRNA and siRNA molecules. An insightful view about individual siRNA and miRNA drugs has been depicted with their present status, which is gaining attention in the therapeutic landscape. The efforts of the biopharmaceuticals are discussed with the status of their preclinical and/or clinical trials. Here, some of the setbacks have been highlighted during the biopharmaceutical development of miRNA and siRNA as individual therapeutics. Finally, a snapshot is illustrated about pharmacokinetics, pharmacodynamics with absorption, distribution, metabolism, and excretion (ADME), which is the fundamental development process of these therapeutics, as well as the delivery system for miRNA- and siRNA-based drugs. äTherapeutic miRNA and siRNA: Moving from Bench to Clinic as Next Gener(epmc).pdf DeepDyve Pubget Overpricing