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10.1016/j.conb.2016.08.003

http://scihub22266oqcxt.onion/10.1016/j.conb.2016.08.003
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C5495096!5495096!27589601
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suck abstract from ncbi


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pmid27589601      Curr+Opin+Neurobiol 2016 ; 41 (ä): 53-61
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  • Microcircuits in respiratory rhythm generation: commonalities with other rhythm generating networks and evolutionary perspectives #MMPMID27589601
  • Ramirez JM; Dashevskiy T; Marlin IA; Baertsch N
  • Curr Opin Neurobiol 2016[Dec]; 41 (ä): 53-61 PMID27589601show ga
  • Rhythmicity is critical for the generation of rhythmic behaviors and higher brain functions. This review discusses common mechanisms of rhythm generation, including the role of synaptic inhibition and excitation, with a focus on the mammalian respiratory network. This network generates three phases of breathing and is highly integrated with brain regions associated with numerous non-ventilatory behaviors. We hypothesize that during evolution multiple rhythmogenic microcircuits were recruited to accommodate the generation of each breathing phase. While these microcircuits relied primarily on excitatory mechanisms, synaptic inhibition became increasingly important to coordinate the different microcircuits and to integrate breathing into a rich behavioral repertoire that links breathing to sensory processing, arousal, and emotions as well as learning and memory.
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