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10.15252/embj.201796999

http://scihub22266oqcxt.onion/10.15252/embj.201796999
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C5494466!5494466!28507224
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suck abstract from ncbi


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pmid28507224      EMBO+J 2017 ; 36 (13): 1806-8
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  • c?MYC mRNA tail tale about glutamine control of transcription #MMPMID28507224
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  • EMBO J 2017[Jul]; 36 (13): 1806-8 PMID28507224show ga
  • Dejure et al (2017) demonstrates an intriguing link between glutamine, c?MYC protein levels, and c?MYC?dependent transcription. Glutamine?dependent c?MYC protein level, which is sensed through the c?MYC mRNA 3??UTR, determines global transcriptional response to glutamine deprivation in HCT116 colon cancer cells. These findings add another layer of complexity to c?MYC's role as a nexus in metabolic regulation.
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