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10.7554/eLife.25014 http://scihub22266oqcxt.onion/10.7554/eLife.25014 C5493435!5493435!28665270     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       eLife 2017 ; 6 (ä): ä Nephropedia Template TP {{tp|p=28665270|t=2017. Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division |pdf=|usr=}}{{28665270}} gab.com Text Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division JO: eLife http://www.kidney.de/pget.php?&tw=1&pmid=28665270 #FOAvip Polarity is a shared feature of most cells. In epithelia, apical-basal polarity often coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the epithelial plane. From a limited set of core building blocks (e.g. the Par complexes for apical-basal polarity and the Frizzled/Dishevelled complex for PCP), a diverse array of polarized cells and tissues are generated. This suggests the existence of little-studied tissue-specific factors that rewire the core polarity modules to the appropriate conformation. In Drosophila sensory organ precursors (SOPs), the core PCP components initiate the planar polarization of apical-basal determinants, ensuring asymmetric division into daughter cells of different fates. We show that Meru, a RASSF9/RASSF10 homologue, is expressed specifically in SOPs, recruited to the posterior cortex by Frizzled/Dishevelled, and in turn polarizes the apical-basal polarity factor Bazooka (Par3). Thus, Meru belongs to a class of proteins that act cell/tissue-specifically to remodel the core polarity machinery.DOI:http://dx.doi.org/10.7554/eLife.25014.001 Twit Text FOAVip Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division ????eLife http://www.kidney.de/pget.php?&tw=1&pmid=28665270 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28665270 #FOAvip English Wikipedia <ref>{{Cite pmid|28665270}}</ref> Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division #MMPMID28665270 Banerjee JJ; Aerne BL; Holder MV; Hauri S; Gstaiger M; Tapon N eLife 2017[]; 6 (ä): ä PMID28665270show ga Polarity is a shared feature of most cells. In epithelia, apical-basal polarity often coexists, and sometimes intersects with planar cell polarity (PCP), which orients cells in the epithelial plane. From a limited set of core building blocks (e.g. the Par complexes for apical-basal polarity and the Frizzled/Dishevelled complex for PCP), a diverse array of polarized cells and tissues are generated. This suggests the existence of little-studied tissue-specific factors that rewire the core polarity modules to the appropriate conformation. In Drosophila sensory organ precursors (SOPs), the core PCP components initiate the planar polarization of apical-basal determinants, ensuring asymmetric division into daughter cells of different fates. We show that Meru, a RASSF9/RASSF10 homologue, is expressed specifically in SOPs, recruited to the posterior cortex by Frizzled/Dishevelled, and in turn polarizes the apical-basal polarity factor Bazooka (Par3). Thus, Meru belongs to a class of proteins that act cell/tissue-specifically to remodel the core polarity machinery.DOI:http://dx.doi.org/10.7554/eLife.25014.001 äMeru couples planar cell polarity with apical-basal polarity during as(epmc).pdf DeepDyve Pubget Overpricing