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10.1016/j.devcel.2017.04.001 http://scihub22266oqcxt.onion/10.1016/j.devcel.2017.04.001 C5492985!5492985!28486129     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dev+Cell 2017 ; 41 (3): 228-41 Nephropedia Template TP {{tp|p=28486129|t=2017. The Canonical Notch Signaling Pathway: Structural And Biochemical Insights Into Shape, Sugar, And Force |pdf=|usr=}}{{28486129}} gab.com Text The Canonical Notch Signaling Pathway: Structural And Biochemical Insights Into Shape, Sugar, And Force JO: Dev Cell http://www.kidney.de/pget.php?&tw=1&pmid=28486129 #FOAvip The Notch signaling pathway relies on a proteolytic cascade to release its transcriptionally active intracellular domain, on force to unfold a protective domain and permit proteolysis, on extracellular domain glycosylation to tune the forces exerted by endocytosed ligands, and on a motley crew of nuclear proteins, chromatin modifiers, ubiquitin ligases, and a few kinases to regulate activity and half-life. Herein we provide a review of recent molecular insights into how Notch signals are triggered and how cell shape affects these events, and use the new insights to illuminate a few perplexing observations. Twit Text FOAVip The Canonical Notch Signaling Pathway: Structural And Biochemical Insights Into Shape, Sugar, And Force ????Dev Cell http://www.kidney.de/pget.php?&tw=1&pmid=28486129 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28486129 #FOAvip English Wikipedia <ref>{{Cite pmid|28486129}}</ref> The Canonical Notch Signaling Pathway: Structural And Biochemical Insights Into Shape, Sugar, And Force #MMPMID28486129 Kovall RA; Gebelein B; Sprinzak D; Kopan R Dev Cell 2017[May]; 41 (3): 228-41 PMID28486129show ga The Notch signaling pathway relies on a proteolytic cascade to release its transcriptionally active intracellular domain, on force to unfold a protective domain and permit proteolysis, on extracellular domain glycosylation to tune the forces exerted by endocytosed ligands, and on a motley crew of nuclear proteins, chromatin modifiers, ubiquitin ligases, and a few kinases to regulate activity and half-life. Herein we provide a review of recent molecular insights into how Notch signals are triggered and how cell shape affects these events, and use the new insights to illuminate a few perplexing observations. äThe Canonical Notch Signaling Pathway: Structural And Biochemical Insi(epmc).pdf DeepDyve Pubget Overpricing