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10.1111/imr.12546 http://scihub22266oqcxt.onion/10.1111/imr.12546 C5492959!5492959 !28658558     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28658558 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Immunol+Rev 2017 ; 278 (1 ): 116-130 Nephropedia Template TP {{tp|p=28658558 |t=2017. The atopic march: current insights into skin barrier dysfunction and epithelial cell-derived cytokines |pdf=|usr=}}{{28658558 }} gab.com Text The atopic march: current insights into skin barrier dysfunction and epithelial cell-derived cytokines JO: Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=28658558 #FOAvip Atopic dermatitis often precedes the development of other atopic diseases. The atopic march describes this temporal relationship in the natural history of atopic diseases. Although the pathophysiological mechanisms that underlie this relationship are poorly understood, epidemiological and genetic data have suggested that the skin might be an important route of sensitization to allergens. Animal models have begun to elucidate how skin barrier defects can lead to systemic allergen sensitization. Emerging data now suggest that epithelial cell-derived cytokines such as thymic stromal lymphopoietin (TSLP), IL-33, and IL-25 may drive the progression from atopic dermatitis to asthma and food allergy. This review focuses on current concepts of the role of skin barrier defects and epithelial cell-derived cytokines in the initiation and maintenance of allergic inflammation and the atopic march. Twit Text FOAVip The atopic march: current insights into skin barrier dysfunction and epithelial cell-derived cytokines ????Immunol Rev http://www.kidney.de/pget.php?&tw=1&pmid=28658558 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28658558 #FOAvip English Wikipedia <ref>{{Cite pmid|28658558 }}</ref> The atopic march: current insights into skin barrier dysfunction and epithelial cell-derived cytokines #MMPMID28658558 Han H ; Roan F ; Ziegler SF Immunol Rev 2017[Jul]; 278 (1 ): 116-130 PMID28658558 show ga Atopic dermatitis often precedes the development of other atopic diseases. The atopic march describes this temporal relationship in the natural history of atopic diseases. Although the pathophysiological mechanisms that underlie this relationship are poorly understood, epidemiological and genetic data have suggested that the skin might be an important route of sensitization to allergens. Animal models have begun to elucidate how skin barrier defects can lead to systemic allergen sensitization. Emerging data now suggest that epithelial cell-derived cytokines such as thymic stromal lymphopoietin (TSLP), IL-33, and IL-25 may drive the progression from atopic dermatitis to asthma and food allergy. This review focuses on current concepts of the role of skin barrier defects and epithelial cell-derived cytokines in the initiation and maintenance of allergic inflammation and the atopic march. |Allergens/immunology [MESH] |Animals [MESH] |Cytokines/metabolism [MESH] |Dermatitis, Atopic/*etiology/*metabolism/pathology/therapy [MESH] |Environment [MESH] |Epithelial Cells/metabolism [MESH] |Genetic Predisposition to Disease [MESH] |Humans [MESH] |Immune Tolerance/immunology [MESH] |Immunization [MESH] |Immunotherapy [MESH]The atopic march: current insights into skin barrier dysfunction and e(epmc).pdf DeepDyve Pubget Overpricing