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10.1186/s12944-017-0521-7 http://scihub22266oqcxt.onion/10.1186/s12944-017-0521-7 C5492776!5492776!28662670     free     free     free       Lipids+Health+Dis 2017 ; 16 (ä): ä Nephropedia Template TP {{tp|p=28662670|t=2017. Lipid Droplets in Health and Disease |pdf=|usr=}}{{28662670}} gab.com Text Lipid Droplets in Health and Disease JO: Lipids Health Dis http://www.kidney.de/pget.php?&tw=1&pmid=28662670 #FOAvip Lipids are essential building blocks synthesized by complex molecular pathways and deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found in almost all organisms, from bacteria to mammals. They are composed of a hydrophobic neutral lipid core surrounding by a phospholipid monolayer membrane with various decorating proteins. Degradation of LDs provide metabolic energy for divergent cellular processes such as membrane synthesis and molecular signaling. Lipolysis and autophagy are two main catabolic pathways of LDs, which regulate lipid metabolism and, thereby, closely engaged in many pathological conditons. In this review, we first provide an overview of the current knowledge on the structural properties and the biogenesis of LDs. We further focus on the recent findings of their catabolic mechanism by lipolysis and autophagy as well as their connection ragarding the regulation and function. Moreover, we discuss the relevance of LDs and their catabolism-dependent pathophysiological conditions. Twit Text FOAVip Lipid Droplets in Health and Disease ????Lipids Health Dis http://www.kidney.de/pget.php?&tw=1&pmid=28662670 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28662670 #FOAvip English Wikipedia <ref>{{Cite pmid|28662670}}</ref> Lipid Droplets in Health and Disease #MMPMID28662670 Onal G; Kutlu O; Gozuacik D; Dokmeci Emre S Lipids Health Dis 2017[]; 16 (ä): ä PMID28662670show ga Lipids are essential building blocks synthesized by complex molecular pathways and deposited as lipid droplets (LDs) in cells. LDs are evolutionary conserved organelles found in almost all organisms, from bacteria to mammals. They are composed of a hydrophobic neutral lipid core surrounding by a phospholipid monolayer membrane with various decorating proteins. Degradation of LDs provide metabolic energy for divergent cellular processes such as membrane synthesis and molecular signaling. Lipolysis and autophagy are two main catabolic pathways of LDs, which regulate lipid metabolism and, thereby, closely engaged in many pathological conditons. In this review, we first provide an overview of the current knowledge on the structural properties and the biogenesis of LDs. We further focus on the recent findings of their catabolic mechanism by lipolysis and autophagy as well as their connection ragarding the regulation and function. Moreover, we discuss the relevance of LDs and their catabolism-dependent pathophysiological conditions. äLipid Droplets in Health and Disease (epmc).pdf DeepDyve Pubget Overpricing