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suck abstract from ncbi


10.1038/nrc.2016.27

http://scihub22266oqcxt.onion/10.1038/nrc.2016.27
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C5491099!5491099!27112207
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suck abstract from ncbi


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pmid27112207      Nat+Rev+Cancer 2016 ; 16 (5): 288-304
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  • New frontiers in translational control of the cancer genome #MMPMID27112207
  • Truitt ML; Ruggero D
  • Nat Rev Cancer 2016[Apr]; 16 (5): 288-304 PMID27112207show ga
  • The past several years have seen dramatic leaps in our understanding of how gene expression is rewired at the translation level during tumorigenesis to support the transformed phenotype. This work has been driven by an explosion in technological advances and is revealing previously unimagined regulatory mechanisms that dictate functional expression of the cancer genome. In this Review we discuss emerging trends and exciting new discoveries that reveal how this translational circuitry contributes to specific aspects of tumorigenesis and cancer cell function, with a particular focus on recent insights into the role of translational control in the adaptive response to oncogenic stress conditions.
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