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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Ann+Anat
2017 ; 211
(ä): 184-201
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gab.com Text
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Structure, genetics and function of the pulmonary associated surfactant proteins
A and D: The extra-pulmonary role of these C type lectins
#MMPMID28351530
Vieira F
; Kung JW
; Bhatti F
Ann Anat
2017[May]; 211
(ä): 184-201
PMID28351530
show ga
The collectins family encompasses several collagenous Ca(2+)-dependent defense
lectins that are described as pathogen recognition molecules. They play an
important role in both adaptive and innate immunity. Surfactant proteins A and D
are two of these proteins which were initially discovered in association with
surfactant in the pulmonary system. The structure, immune and inflammatory
functions, and genetic variations have been well described in relation to their
roles, function and pathophysiology in the pulmonary system. Subsequently, these
proteins have been discovered in a wide range of other organs and organ systems.
The role of these proteins outside the pulmonary system is currently an active
area of research. This review intends to provide a current overview of the
genetics, structure and extra-pulmonary functions of the surfactant collectin
proteins.
|Animals
[MESH]
|Humans
[MESH]
|Immunity, Innate/*genetics/*immunology
[MESH]
|Polymorphism, Single Nucleotide/genetics
[MESH]
|Pulmonary Surfactant-Associated Protein A/chemistry/*genetics/*immunology
[MESH]
|Pulmonary Surfactant-Associated Protein D/chemistry/*genetics/*immunology
[MESH]