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10.1186/s12916-017-0871-z http://scihub22266oqcxt.onion/10.1186/s12916-017-0871-z C5488376!5488376!28655311     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Med 2017 ; 15 (ä): ä Nephropedia Template TP {{tp|p=28655311|t=2017. Diagnostic delay for giant cell arteritis ? a systematic review and meta-analysis |pdf=|usr=}}{{28655311}} gab.com Text Diagnostic delay for giant cell arteritis a systematic review and meta-analysis JO: BMC Med http://www.kidney.de/pget.php?&tw=1&pmid=28655311 #FOAvip Background: Giant cell arteritis (GCA), if untreated, can lead to blindness and stroke. The study?s objectives were to (1) determine a new evidence-based benchmark of the extent of diagnostic delay for GCA and (2) examine the role of GCA-specific characteristics on diagnostic delay. Methods: Medical literature databases were searched from inception to November 2015. Articles were included if reporting a time-period of diagnostic delay between onset of GCA symptoms and diagnosis. Two reviewers assessed the quality of the final articles and extracted data from these. Random-effects meta-analysis was used to pool the mean time-period (95% confidence interval (CI)) between GCA symptom onset and diagnosis, and the delay observed for GCA-specific characteristics. Heterogeneity was assessed by I2 and by 95% prediction interval (PI). Results: Of 4128 articles initially identified, 16 provided data for meta-analysis. Mean diagnostic delay was 9.0 weeks (95% CI, 6.5 to 11.4) between symptom onset and GCA diagnosis (I2?=?96.0%; P?<?0.001; 95% PI, 0 to 19.2 weeks). Patients with a cranial presentation of GCA received a diagnosis after 7.7 (95% CI, 2.7 to 12.8) weeks (I2?=?98.4%; P?<?0.001; 95% PI, 0 to 27.6 weeks) and those with non-cranial GCA after 17.6 (95% CI, 9.7 to 25.5) weeks (I2?=?96.6%; P?<?0.001; 95% PI, 0 to 46.1 weeks). Conclusions: The mean delay from symptom onset to GCA diagnosis was 9 weeks, or longer when cranial symptoms were absent. Our research provides an evidence-based benchmark for diagnostic delay of GCA and supports the need for improved public awareness and fast-track diagnostic pathways. Electronic supplementary material: The online version of this article (doi:10.1186/s12916-017-0871-z) contains supplementary material, which is available to authorized users. Twit Text FOAVip Diagnostic delay for giant cell arteritis a systematic review and meta-analysis ????BMC Med http://www.kidney.de/pget.php?&tw=1&pmid=28655311 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28655311 #FOAvip English Wikipedia <ref>{{Cite pmid|28655311}}</ref> Diagnostic delay for giant cell arteritis ? a systematic review and meta-analysis #MMPMID28655311 Prior JA; Ranjbar H; Belcher J; Mackie SL; Helliwell T; Liddle J; Mallen CD BMC Med 2017[]; 15 (ä): ä PMID28655311show ga Background: Giant cell arteritis (GCA), if untreated, can lead to blindness and stroke. The study?s objectives were to (1) determine a new evidence-based benchmark of the extent of diagnostic delay for GCA and (2) examine the role of GCA-specific characteristics on diagnostic delay. Methods: Medical literature databases were searched from inception to November 2015. Articles were included if reporting a time-period of diagnostic delay between onset of GCA symptoms and diagnosis. Two reviewers assessed the quality of the final articles and extracted data from these. Random-effects meta-analysis was used to pool the mean time-period (95% confidence interval (CI)) between GCA symptom onset and diagnosis, and the delay observed for GCA-specific characteristics. Heterogeneity was assessed by I2 and by 95% prediction interval (PI). Results: Of 4128 articles initially identified, 16 provided data for meta-analysis. Mean diagnostic delay was 9.0 weeks (95% CI, 6.5 to 11.4) between symptom onset and GCA diagnosis (I2?=?96.0%; P? äDiagnostic delay for giant cell arteritis ? a systematic review and me(epmc).pdf DeepDyve Pubget Overpricing