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10.1186/s13059-017-1253-8 http://scihub22266oqcxt.onion/10.1186/s13059-017-1253-8 C5488307!5488307 !28655341     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28655341 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Genome+Biol 2017 ; 18 (1 ): 125 Nephropedia Template TP {{tp|p=28655341 |t=2017. Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours |pdf=|usr=}}{{28655341 }} gab.com Text Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours JO: Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=28655341 #FOAvip Chromosomal rearrangements occur constitutionally in the general population and somatically in the majority of cancers. Detection of balanced rearrangements, such as reciprocal translocations and inversions, is troublesome, which is particularly detrimental in oncology where rearrangements play diagnostic and prognostic roles. Here we describe the use of Hi-C as a tool for detection of both balanced and unbalanced chromosomal rearrangements in primary human tumour samples, with the potential to define chromosome breakpoints to bp resolution. In addition, we show copy number profiles can also be obtained from the same data, all at a significantly lower cost than standard sequencing approaches. Twit Text FOAVip Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours ????Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=28655341 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28655341 #FOAvip English Wikipedia <ref>{{Cite pmid|28655341 }}</ref> Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours #MMPMID28655341 Harewood L ; Kishore K ; Eldridge MD ; Wingett S ; Pearson D ; Schoenfelder S ; Collins VP ; Fraser P Genome Biol 2017[Jun]; 18 (1 ): 125 PMID28655341 show ga Chromosomal rearrangements occur constitutionally in the general population and somatically in the majority of cancers. Detection of balanced rearrangements, such as reciprocal translocations and inversions, is troublesome, which is particularly detrimental in oncology where rearrangements play diagnostic and prognostic roles. Here we describe the use of Hi-C as a tool for detection of both balanced and unbalanced chromosomal rearrangements in primary human tumour samples, with the potential to define chromosome breakpoints to bp resolution. In addition, we show copy number profiles can also be obtained from the same data, all at a significantly lower cost than standard sequencing approaches. |*Translocation, Genetic [MESH] |Chromosome Aberrations [MESH] |Chromosome Breakpoints [MESH] |Chromosome Inversion/genetics [MESH] |DNA Copy Number Variations/*genetics [MESH] |Humans [MESH] |In Situ Hybridization, Fluorescence [MESH]Hi-C as a tool for precise detection and characterisation of chromosom(epmc).pdf DeepDyve Pubget Overpricing