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10.3390/antiox6020023 http://scihub22266oqcxt.onion/10.3390/antiox6020023 C5488003!5488003!28333068     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Antioxidants+(Basel) 2017 ; 6 (2): ä Nephropedia Template TP {{tp|p=28333068|t=2017. Effects of Reactive Oxygen Species on Tubular Transport along the Nephron |pdf=|usr=}}{{28333068}} gab.com Text Effects of Reactive Oxygen Species on Tubular Transport along the Nephron JO: Antioxidants (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28333068 #FOAvip Reactive oxygen species (ROS) are oxygen-containing molecules naturally occurring in both inorganic and biological chemical systems. Due to their high reactivity and potentially damaging effects to biomolecules, cells express a battery of enzymes to rapidly metabolize them to innocuous intermediaries. Initially, ROS were considered by biologists as dangerous byproducts of respiration capable of causing oxidative stress, a condition in which overproduction of ROS leads to a reduction in protective molecules and enzymes and consequent damage to lipids, proteins, and DNA. In fact, ROS are used by immune systems to kill virus and bacteria, causing inflammation and local tissue damage. Today, we know that the functions of ROS are not so limited, and that they also act as signaling molecules mediating processes as diverse as gene expression, mechanosensation, and epithelial transport. In the kidney, ROS such as nitric oxide (NO), superoxide (O2?), and their derivative molecules hydrogen peroxide (H2O2) and peroxynitrite (ONO2?) regulate solute and water reabsorption, which is vital to maintain electrolyte homeostasis and extracellular fluid volume. This article reviews the effects of NO, O2?, ONO2?, and H2O2 on water and electrolyte reabsorption in proximal tubules, thick ascending limbs, and collecting ducts, and the effects of NO and O2? in the macula densa on tubuloglomerular feedback. Twit Text FOAVip Effects of Reactive Oxygen Species on Tubular Transport along the Nephron ????Antioxidants (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28333068 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28333068 #FOAvip English Wikipedia <ref>{{Cite pmid|28333068}}</ref> Effects of Reactive Oxygen Species on Tubular Transport along the Nephron #MMPMID28333068 Gonzalez-Vicente A; Garvin JL Antioxidants (Basel) 2017[Jun]; 6 (2): ä PMID28333068show ga Reactive oxygen species (ROS) are oxygen-containing molecules naturally occurring in both inorganic and biological chemical systems. Due to their high reactivity and potentially damaging effects to biomolecules, cells express a battery of enzymes to rapidly metabolize them to innocuous intermediaries. Initially, ROS were considered by biologists as dangerous byproducts of respiration capable of causing oxidative stress, a condition in which overproduction of ROS leads to a reduction in protective molecules and enzymes and consequent damage to lipids, proteins, and DNA. In fact, ROS are used by immune systems to kill virus and bacteria, causing inflammation and local tissue damage. Today, we know that the functions of ROS are not so limited, and that they also act as signaling molecules mediating processes as diverse as gene expression, mechanosensation, and epithelial transport. In the kidney, ROS such as nitric oxide (NO), superoxide (O2?), and their derivative molecules hydrogen peroxide (H2O2) and peroxynitrite (ONO2?) regulate solute and water reabsorption, which is vital to maintain electrolyte homeostasis and extracellular fluid volume. This article reviews the effects of NO, O2?, ONO2?, and H2O2 on water and electrolyte reabsorption in proximal tubules, thick ascending limbs, and collecting ducts, and the effects of NO and O2? in the macula densa on tubuloglomerular feedback. äEffects of Reactive Oxygen Species on Tubular Transport along the Neph(epmc).pdf DeepDyve Pubget Overpricing