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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Chem+Rev 2017 ; 117 (11): 7276-330 Nephropedia Template TP
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Unraveling the Thousand Word Picture: An Introduction to Super-Resolution Data Analysis #MMPMID28414216
Lee A; Tsekouras K; Calderon C; Bustamante C; Pressé S
Chem Rev 2017[Jun]; 117 (11): 7276-330 PMID28414216show ga
Super-resolution microscopy provides direct insight into fundamental biological processes occurring at length scales smaller than light?s diffraction limit. The analysis of data at such scales has brought statistical and machine learning methods into the mainstream. Here we provide a survey of data analysis methods starting from an overview of basic statistical techniques underlying the analysis of super-resolution and, more broadly, imaging data. We subsequently break down the analysis of super-resolution data into four problems: the localization problem, the counting problem, the linking problem, and what we?ve termed the interpretation problem.