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10.3390/ijerph14060627 http://scihub22266oqcxt.onion/10.3390/ijerph14060627 C5486313!5486313 !28604590     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28604590 &cmd=llinks): Failed to open stream: HTTP request failed! 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Lithium in Drinking Water and Incidence of Suicide: A Nationwide Individual-Level Cohort Study with 22 Years of Follow-Up |pdf=|usr=}}{{28604590 }} gab.com Text Lithium in Drinking Water and Incidence of Suicide: A Nationwide Individual-Level Cohort Study with 22 Years of Follow-Up JO: Int J Environ Res Public Health http://www.kidney.de/pget.php?&tw=1&pmid=28604590 #FOAvip Suicide is a major public health concern. High-dose lithium is used to stabilize mood and prevent suicide in patients with affective disorders. Lithium occurs naturally in drinking water worldwide in much lower doses, but with large geographical variation. Several studies conducted at an aggregate level have suggested an association between lithium in drinking water and a reduced risk of suicide; however, a causal relation is uncertain. Individual-level register-based data on the entire Danish adult population (3.7 million individuals) from 1991 to 2012 were linked with a moving five-year time-weighted average (TWA) lithium exposure level from drinking water hypothesizing an inverse relationship. The mean lithium level was 11.6 ?g/L ranging from 0.6 to 30.7 ?g/L. The suicide rate decreased from 29.7 per 100,000 person-years at risk in 1991 to 18.4 per 100,000 person-years in 2012. We found no significant indication of an association between increasing five-year TWA lithium exposure level and decreasing suicide rate. The comprehensiveness of using individual-level data and spatial analyses with 22 years of follow-up makes a pronounced contribution to previous findings. Our findings demonstrate that there does not seem to be a protective effect of exposure to lithium on the incidence of suicide with levels below 31 ?g/L in drinking water. Twit Text FOAVip Lithium in Drinking Water and Incidence of Suicide: A Nationwide Individual-Level Cohort Study with 22 Years of Follow-Up ????Int J Environ Res Public Health http://www.kidney.de/pget.php?&tw=1&pmid=28604590 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28604590 #FOAvip English Wikipedia <ref>{{Cite pmid|28604590 }}</ref> Lithium in Drinking Water and Incidence of Suicide: A Nationwide Individual-Level Cohort Study with 22 Years of Follow-Up #MMPMID28604590 Knudsen NN ; Schullehner J ; Hansen B ; Jørgensen LF ; Kristiansen SM ; Voutchkova DD ; Gerds TA ; Andersen PK ; Bihrmann K ; Grønbæk M ; Kessing LV ; Ersbøll AK Int J Environ Res Public Health 2017[Jun]; 14 (6 ): ä PMID28604590 show ga Suicide is a major public health concern. High-dose lithium is used to stabilize mood and prevent suicide in patients with affective disorders. Lithium occurs naturally in drinking water worldwide in much lower doses, but with large geographical variation. Several studies conducted at an aggregate level have suggested an association between lithium in drinking water and a reduced risk of suicide; however, a causal relation is uncertain. Individual-level register-based data on the entire Danish adult population (3.7 million individuals) from 1991 to 2012 were linked with a moving five-year time-weighted average (TWA) lithium exposure level from drinking water hypothesizing an inverse relationship. The mean lithium level was 11.6 ?g/L ranging from 0.6 to 30.7 ?g/L. The suicide rate decreased from 29.7 per 100,000 person-years at risk in 1991 to 18.4 per 100,000 person-years in 2012. We found no significant indication of an association between increasing five-year TWA lithium exposure level and decreasing suicide rate. The comprehensiveness of using individual-level data and spatial analyses with 22 years of follow-up makes a pronounced contribution to previous findings. Our findings demonstrate that there does not seem to be a protective effect of exposure to lithium on the incidence of suicide with levels below 31 ?g/L in drinking water. |*Suicide [MESH] |Adult [MESH] |Aged [MESH] |Aged, 80 and over [MESH] |Denmark/epidemiology [MESH] |Drinking Water/*analysis [MESH] |Female [MESH] |Follow-Up Studies [MESH] |Humans [MESH] |Incidence [MESH] |Lithium/*analysis [MESH] |Male [MESH] |Middle Aged [MESH] |Spatial Analysis [MESH] |Water Pollutants, Chemical/*analysis [MESH]Lithium in Drinking Water and Incidence of Suicide: A Nationwide Indiv(epmc).pdf DeepDyve Pubget Overpricing