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10.3390/ijms18061185

http://scihub22266oqcxt.onion/10.3390/ijms18061185
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C5486008!5486008!28574477
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suck abstract from ncbi


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pmid28574477      Int+J+Mol+Sci 2017 ; 18 (6): ä
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  • Utilizing Zebrafish Visual Behaviors in Drug Screening for Retinal Degeneration #MMPMID28574477
  • Ganzen L; Venkatraman P; Pang CP; Leung YF; Zhang M
  • Int J Mol Sci 2017[Jun]; 18 (6): ä PMID28574477show ga
  • Zebrafish are a popular vertebrate model in drug discovery. They produce a large number of small and rapidly-developing embryos. These embryos display rich visual-behaviors that can be used to screen drugs for treating retinal degeneration (RD). RD comprises blinding diseases such as Retinitis Pigmentosa, which affects 1 in 4000 people. This disease has no definitive cure, emphasizing an urgency to identify new drugs. In this review, we will discuss advantages, challenges, and research developments in using zebrafish behaviors to screen drugs in vivo. We will specifically discuss a visual-motor response that can potentially expedite discovery of new RD drugs.
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