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10.3390/genes8060150 http://scihub22266oqcxt.onion/10.3390/genes8060150 C5485514!5485514!28538662     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+(Basel) 2017 ; 8 (6): ä Nephropedia Template TP {{tp|p=28538662|t=2017. Maternal Factors that Induce Epigenetic Changes Contribute to Neurological Disorders in Offspring |pdf=|usr=}}{{28538662}} gab.com Text Maternal Factors that Induce Epigenetic Changes Contribute to Neurological Disorders in Offspring JO: Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28538662 #FOAvip It is well established that the regulation of epigenetic factors, including chromatic reorganization, histone modifications, DNA methylation, and miRNA regulation, is critical for the normal development and functioning of the human brain. There are a number of maternal factors influencing epigenetic pathways such as lifestyle, including diet, alcohol consumption, and smoking, as well as age and infections (viral or bacterial). Genetic and metabolic alterations such as obesity, gestational diabetes mellitus (GDM), and thyroidism alter epigenetic mechanisms, thereby contributing to neurodevelopmental disorders (NDs) such as embryonic neural tube defects (NTDs), autism, Down?s syndrome, Rett syndrome, and later onset of neuropsychological deficits. This review comprehensively describes the recent findings in the epigenetic landscape contributing to altered molecular profiles resulting in NDs. Furthermore, we will discuss potential avenues for future research to identify diagnostic markers and therapeutic epi-drugs to reverse these abnormalities in the brain as epigenetic marks are plastic and reversible in nature. Twit Text FOAVip Maternal Factors that Induce Epigenetic Changes Contribute to Neurological Disorders in Offspring ????Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28538662 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28538662 #FOAvip English Wikipedia <ref>{{Cite pmid|28538662}}</ref> Maternal Factors that Induce Epigenetic Changes Contribute to Neurological Disorders in Offspring #MMPMID28538662 Banik A; Kandilya D; Ramya S; Stünkel W; Chong YS; Dheen ST Genes (Basel) 2017[Jun]; 8 (6): ä PMID28538662show ga It is well established that the regulation of epigenetic factors, including chromatic reorganization, histone modifications, DNA methylation, and miRNA regulation, is critical for the normal development and functioning of the human brain. There are a number of maternal factors influencing epigenetic pathways such as lifestyle, including diet, alcohol consumption, and smoking, as well as age and infections (viral or bacterial). Genetic and metabolic alterations such as obesity, gestational diabetes mellitus (GDM), and thyroidism alter epigenetic mechanisms, thereby contributing to neurodevelopmental disorders (NDs) such as embryonic neural tube defects (NTDs), autism, Down?s syndrome, Rett syndrome, and later onset of neuropsychological deficits. This review comprehensively describes the recent findings in the epigenetic landscape contributing to altered molecular profiles resulting in NDs. Furthermore, we will discuss potential avenues for future research to identify diagnostic markers and therapeutic epi-drugs to reverse these abnormalities in the brain as epigenetic marks are plastic and reversible in nature. äMaternal Factors that Induce Epigenetic Changes Contribute to Neurolog(epmc).pdf DeepDyve Pubget Overpricing