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10.1038/s41598-017-01061-3 http://scihub22266oqcxt.onion/10.1038/s41598-017-01061-3 C5484668!5484668!28652617     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2017 ; 7 (ä): ä Nephropedia Template TP {{tp|p=28652617|t=2017. Prognostic value of CD146 in solid tumor: A Systematic Review and Meta-analysis |pdf=|usr=}}{{28652617}} gab.com Text Prognostic value of CD146 in solid tumor: A Systematic Review and Meta-analysis JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28652617 #FOAvip CD146, also known as melanoma cell adhesion molecule, was initially identified as a marker of melanoma progression and metastasis. Recently many clinical studies investigated overexpression of CD146 predict poor prognosis of solid tumor, however, the results was inconclusive, partly due to small numbers of patients included. This present meta-analysis was therefore performed utilizing the results of all clinical studies concerned to determine the prognostic value of CD146 expression in solid tumors. Relevant articles were identified through searching the PubMed, Web of Science and Embase database. In this meta-analysis, 12 studies involving 2,694 participants were included, and we drew the conclusion that strong significant associations between CD146 expression and all endpoints: overall survival (OS) [hazard ratio (HR)?=?2.496, 95% confidence interval (95% CI) 2.115?2.946], time to progression (TTP) (HR?=?2.445, 95% CI 1.975?3.027). Furthermore, the subgroup analysis revealed that the associations between CD146 overexpression and the outcome endpoints (OS or TTP) were significant in Mongoloid patients and Caucasian patients, as well in patients with lung cancer and digestive system cancer. In conclusion, these results showed that high CD146 was associated with poor survival in human solid tumors. CD146 may be a valuable prognosis predictive biomarker; nevertheless, whether CD146 could be a potential therapeutic target in human solid tumors needs to be further studied. Twit Text FOAVip Prognostic value of CD146 in solid tumor: A Systematic Review and Meta-analysis ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28652617 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28652617 #FOAvip English Wikipedia <ref>{{Cite pmid|28652617}}</ref> Prognostic value of CD146 in solid tumor: A Systematic Review and Meta-analysis #MMPMID28652617 Zeng P; Li H; Lu PH; Zhou LN; Tang M; Liu CY; Chen MB Sci Rep 2017[]; 7 (ä): ä PMID28652617show ga CD146, also known as melanoma cell adhesion molecule, was initially identified as a marker of melanoma progression and metastasis. Recently many clinical studies investigated overexpression of CD146 predict poor prognosis of solid tumor, however, the results was inconclusive, partly due to small numbers of patients included. This present meta-analysis was therefore performed utilizing the results of all clinical studies concerned to determine the prognostic value of CD146 expression in solid tumors. Relevant articles were identified through searching the PubMed, Web of Science and Embase database. In this meta-analysis, 12 studies involving 2,694 participants were included, and we drew the conclusion that strong significant associations between CD146 expression and all endpoints: overall survival (OS) [hazard ratio (HR)?=?2.496, 95% confidence interval (95% CI) 2.115?2.946], time to progression (TTP) (HR?=?2.445, 95% CI 1.975?3.027). Furthermore, the subgroup analysis revealed that the associations between CD146 overexpression and the outcome endpoints (OS or TTP) were significant in Mongoloid patients and Caucasian patients, as well in patients with lung cancer and digestive system cancer. In conclusion, these results showed that high CD146 was associated with poor survival in human solid tumors. CD146 may be a valuable prognosis predictive biomarker; nevertheless, whether CD146 could be a potential therapeutic target in human solid tumors needs to be further studied. äPrognostic value of CD146 in solid tumor: A Systematic Review and Meta(epmc).pdf DeepDyve Pubget Overpricing