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10.1186/s40364-017-0102-y http://scihub22266oqcxt.onion/10.1186/s40364-017-0102-y C5482931!5482931!28652918     free     free     free       Biomark+Res 2017 ; 5 (ä): ä Nephropedia Template TP {{tp|p=28652918|t=2017. Engineering CAR-T cells |pdf=|usr=}}{{28652918}} gab.com Text Engineering CAR-T cells JO: Biomark Res http://www.kidney.de/pget.php?&tw=1&pmid=28652918 #FOAvip Chimeric antigen receptor redirected T cells (CAR-T cells) have achieved inspiring outcomes in patients with B cell malignancies, and are now being investigated in other hematologic malignancies and solid tumors. CAR-T cells are generated by the T cells from patients? or donors? blood. After the T cells are expanded and genetically modified, they are reinfused into the patients. However, many challenges still need to be resolved in order for this technology to gain widespread adoption. In this review, we first discuss the structure and evolution of chimeric antigen receptors. We then report on the tools used for production of CAR-T cells. Finally, we address the challenges posed by CAR-T cells. Twit Text FOAVip Engineering CAR-T cells ????Biomark Res http://www.kidney.de/pget.php?&tw=1&pmid=28652918 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28652918 #FOAvip English Wikipedia <ref>{{Cite pmid|28652918}}</ref> Engineering CAR-T cells #MMPMID28652918 Zhang C; Liu J; Zhong JF; Zhang X Biomark Res 2017[]; 5 (ä): ä PMID28652918show ga Chimeric antigen receptor redirected T cells (CAR-T cells) have achieved inspiring outcomes in patients with B cell malignancies, and are now being investigated in other hematologic malignancies and solid tumors. CAR-T cells are generated by the T cells from patients? or donors? blood. After the T cells are expanded and genetically modified, they are reinfused into the patients. However, many challenges still need to be resolved in order for this technology to gain widespread adoption. In this review, we first discuss the structure and evolution of chimeric antigen receptors. We then report on the tools used for production of CAR-T cells. Finally, we address the challenges posed by CAR-T cells. äEngineering CAR-T cells (epmc).pdf DeepDyve Pubget Overpricing