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10.4155/fsoa-2016-0089 http://scihub22266oqcxt.onion/10.4155/fsoa-2016-0089 C5481812!5481812!28670466     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Future+Sci+OA 2017 ; 3 (2): ä Nephropedia Template TP {{tp|p=28670466|t=2017. Maintenance of head and neck tumor on-chip: gateway to personalized treatment?|pdf=|usr=}}{{28670466}} gab.com Text Maintenance of head and neck tumor on-chip: gateway to personalized treatment JO: Future Sci OA http://www.kidney.de/pget.php?&tw=1&pmid=28670466 #FOAvip Aim:: Head and neck squamous cell carcinomas (HNSCC) are solid tumors with low overall survival (40?60%). In a move toward personalized medicine, maintenance of tumor biopsies in microfluidic tissue culture devices is being developed. Methodology/results:: HNSCC (n = 15) was dissected (5?10 mg) and either analyzed immediately or cultured in a microfluidic device (37°C) for 48 h. No difference was observed in morphology between pre- and postculture specimens. Dissociated samples were analyzed using trypan blue exclusion (viability), propidium iodide flow cytometry (death) and MTS assay (proliferation) with no significant difference observed highlighting tissue maintenance. Computational fluid dynamics showed laminar flow within the system. Conclusion:: The microfluidic culture system successfully maintained HNSCC for 48 h, the culture system will allow testing of different treatment modalities with response monitoring. Twit Text FOAVip Maintenance of head and neck tumor on-chip: gateway to personalized treatment ????Future Sci OA http://www.kidney.de/pget.php?&tw=1&pmid=28670466 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28670466 #FOAvip English Wikipedia <ref>{{Cite pmid|28670466}}</ref> Maintenance of head and neck tumor on-chip: gateway to personalized treatment? #MMPMID28670466 Bower R; Green VL; Kuvshinova E; Kuvshinov D; Karsai L; Crank ST; Stafford ND; Greenman J Future Sci OA 2017[Jun]; 3 (2): ä PMID28670466show ga Aim:: Head and neck squamous cell carcinomas (HNSCC) are solid tumors with low overall survival (40?60%). In a move toward personalized medicine, maintenance of tumor biopsies in microfluidic tissue culture devices is being developed. Methodology/results:: HNSCC (n = 15) was dissected (5?10 mg) and either analyzed immediately or cultured in a microfluidic device (37°C) for 48 h. No difference was observed in morphology between pre- and postculture specimens. Dissociated samples were analyzed using trypan blue exclusion (viability), propidium iodide flow cytometry (death) and MTS assay (proliferation) with no significant difference observed highlighting tissue maintenance. Computational fluid dynamics showed laminar flow within the system. Conclusion:: The microfluidic culture system successfully maintained HNSCC for 48 h, the culture system will allow testing of different treatment modalities with response monitoring. äMaintenance of head and neck tumor on-chip: gateway to personalized tr(epmc).pdf DeepDyve Pubget Overpricing