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10.1038/s41598-017-03344-1 http://scihub22266oqcxt.onion/10.1038/s41598-017-03344-1 C5481381!5481381!28642464     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2017 ; 7 (ä): ä Nephropedia Template TP {{tp|p=28642464|t=2017. Serum C3 and Renal Outcome in Patients with Primary Focal Segmental Glomerulosclerosis |pdf=|usr=}}{{28642464}} gab.com Text Serum C3 and Renal Outcome in Patients with Primary Focal Segmental Glomerulosclerosis JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28642464 #FOAvip The role of complement (C) in the pathogenesis or progression of focal segmental glomerulosclerosis (FSGS) is uncertain. The present study assessed the relationship between serum C3, the baseline characteristics, and the progression of FSGS in the cohort and identified the clinical implications of serum C3 levels in patients with FSGS. Compared to the patients with C3???85?mg/dL (N?=?474), those with C3?<?85?mg/dL (N?=?117) presented a higher level of serum creatinine, lower levels of eGFR, hemoglobin, proteinuria, triglyceride, cholesterol, IgA, as well as, severe tubulointerstitial injury (TI). Of the 221 patients with a mean follow-up of 53.3 months, the risk of reaching end-stage renal disease (ESRD) was significantly higher in patients with low serum C3 level (p?<?0.001). An additional 40 patients with primary FSGS revealed a significant correlation between MAC and AP (p?=?0.003), MAC and serum C3 (p?=?0.018), and AP and serum C3 (p?=?0.028). Compared to patients with none-to-mild TI, those with moderate-to-severe TI exhibited a lower level of serum C3 and AP, and a higher level of serum MAC. In conclusion, complement activation occurring in patients with FSGS is associated with clinical and histological severities. Low serum C3 was an independent risk factor for poor renal outcome in patients with FSGS. Twit Text FOAVip Serum C3 and Renal Outcome in Patients with Primary Focal Segmental Glomerulosclerosis ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28642464 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28642464 #FOAvip English Wikipedia <ref>{{Cite pmid|28642464}}</ref> Serum C3 and Renal Outcome in Patients with Primary Focal Segmental Glomerulosclerosis #MMPMID28642464 Liu J; Xie J; Zhang X; Tong J; Hao X; Ren H; Wang W; Chen N Sci Rep 2017[]; 7 (ä): ä PMID28642464show ga The role of complement (C) in the pathogenesis or progression of focal segmental glomerulosclerosis (FSGS) is uncertain. The present study assessed the relationship between serum C3, the baseline characteristics, and the progression of FSGS in the cohort and identified the clinical implications of serum C3 levels in patients with FSGS. Compared to the patients with C3???85?mg/dL (N?=?474), those with C3? äSerum C3 and Renal Outcome in Patients with Primary Focal Segmental Gl(epmc).pdf DeepDyve Pubget Overpricing