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10.3762/bjoc.13.111 http://scihub22266oqcxt.onion/10.3762/bjoc.13.111 C5480338!5480338!28684991     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Beilstein+J+Org+Chem 2017 ; 13 (ä): 1119-35 Nephropedia Template TP {{tp|p=28684991|t=2017. From chemical metabolism to life: the origin of the genetic coding process |pdf=|usr=}}{{28684991}} gab.com Text From chemical metabolism to life: the origin of the genetic coding process JO: Beilstein J Org Chem http://www.kidney.de/pget.php?&tw=1&pmid=28684991 #FOAvip Looking for origins is so much rooted in ideology that most studies reflect opinions that fail to explore the first realistic scenarios. To be sure, trying to understand the origins of life should be based on what we know of current chemistry in the solar system and beyond. There, amino acids and very small compounds such as carbon dioxide, dihydrogen or dinitrogen and their immediate derivatives are ubiquitous. Surface-based chemical metabolism using these basic chemicals is the most likely beginning in which amino acids, coenzymes and phosphate-based small carbon molecules were built up. Nucleotides, and of course RNAs, must have come to being much later. As a consequence, the key question to account for life is to understand how chemical metabolism that began with amino acids progressively shaped into a coding process involving RNAs. Here I explore the role of building up complementarity rules as the first information-based process that allowed for the genetic code to emerge, after RNAs were substituted to surfaces to carry over the basic metabolic pathways that drive the pursuit of life. Twit Text FOAVip From chemical metabolism to life: the origin of the genetic coding process ????Beilstein J Org Chem http://www.kidney.de/pget.php?&tw=1&pmid=28684991 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28684991 #FOAvip English Wikipedia <ref>{{Cite pmid|28684991}}</ref> From chemical metabolism to life: the origin of the genetic coding process #MMPMID28684991 Danchin A Beilstein J Org Chem 2017[]; 13 (ä): 1119-35 PMID28684991show ga Looking for origins is so much rooted in ideology that most studies reflect opinions that fail to explore the first realistic scenarios. To be sure, trying to understand the origins of life should be based on what we know of current chemistry in the solar system and beyond. There, amino acids and very small compounds such as carbon dioxide, dihydrogen or dinitrogen and their immediate derivatives are ubiquitous. Surface-based chemical metabolism using these basic chemicals is the most likely beginning in which amino acids, coenzymes and phosphate-based small carbon molecules were built up. Nucleotides, and of course RNAs, must have come to being much later. As a consequence, the key question to account for life is to understand how chemical metabolism that began with amino acids progressively shaped into a coding process involving RNAs. Here I explore the role of building up complementarity rules as the first information-based process that allowed for the genetic code to emerge, after RNAs were substituted to surfaces to carry over the basic metabolic pathways that drive the pursuit of life. äFrom chemical metabolism to life: the origin of the genetic coding pro(epmc).pdf DeepDyve Pubget Overpricing