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10.1155/2017/8060949 http://scihub22266oqcxt.onion/10.1155/2017/8060949 C5478868!5478868!28680532     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oxid+Med+Cell+Longev 2017 ; 2017 (ä): ä Nephropedia Template TP {{tp|p=28680532|t=2017. Mitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome |pdf=|usr=}}{{28680532}} gab.com Text Mitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome JO: Oxid Med Cell Longev http://www.kidney.de/pget.php?&tw=1&pmid=28680532 #FOAvip Mitochondria preserve very complex and distinctively unique machinery to maintain and express the content of mitochondrial DNA (mtDNA). Similar to chromosomes, mtDNA is packaged into discrete mtDNA-protein complexes referred to as a nucleoid. In addition to its role as a mtDNA shield, over 50 nucleoid-associated proteins play roles in mtDNA maintenance and gene expression through either temporary or permanent association with mtDNA or other nucleoid-associated proteins. The number of mtDNA(s) contained within a single nucleoid is a fundamental question but remains a somewhat controversial issue. Disturbance in nucleoid components and mutations in mtDNA were identified as significant in various diseases, including carcinogenesis. Significant interest in the nucleoid structure and its regulation has been stimulated in relation to mitochondrial diseases, which encompass diseases in multicellular organisms and are associated with accumulation of numerous mutations in mtDNA. In this review, mitochondrial nucleoid structure, nucleoid-associated proteins, and their regulatory roles in mitochondrial metabolism are briefly addressed to provide an overview of the emerging research field involving mitochondrial biology. Twit Text FOAVip Mitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome ????Oxid Med Cell Longev http://www.kidney.de/pget.php?&tw=1&pmid=28680532 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28680532 #FOAvip English Wikipedia <ref>{{Cite pmid|28680532}}</ref> Mitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome #MMPMID28680532 Lee SR; Han J Oxid Med Cell Longev 2017[]; 2017 (ä): ä PMID28680532show ga Mitochondria preserve very complex and distinctively unique machinery to maintain and express the content of mitochondrial DNA (mtDNA). Similar to chromosomes, mtDNA is packaged into discrete mtDNA-protein complexes referred to as a nucleoid. In addition to its role as a mtDNA shield, over 50 nucleoid-associated proteins play roles in mtDNA maintenance and gene expression through either temporary or permanent association with mtDNA or other nucleoid-associated proteins. The number of mtDNA(s) contained within a single nucleoid is a fundamental question but remains a somewhat controversial issue. Disturbance in nucleoid components and mutations in mtDNA were identified as significant in various diseases, including carcinogenesis. Significant interest in the nucleoid structure and its regulation has been stimulated in relation to mitochondrial diseases, which encompass diseases in multicellular organisms and are associated with accumulation of numerous mutations in mtDNA. In this review, mitochondrial nucleoid structure, nucleoid-associated proteins, and their regulatory roles in mitochondrial metabolism are briefly addressed to provide an overview of the emerging research field involving mitochondrial biology. äMitochondrial Nucleoid: Shield and Switch of the Mitochondrial Genome (epmc).pdf DeepDyve Pubget Overpricing