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10.2169/internalmedicine.56.7862

http://scihub22266oqcxt.onion/10.2169/internalmedicine.56.7862
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suck abstract from ncbi


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pmid28458317
      Intern+Med 2017 ; 56 (9 ): 1085-1088
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  • Long-term Eculizumab Treatment Contributes to Recovery from End-stage Renal Disease Caused by Atypical Hemolytic Uremic Syndrome #MMPMID28458317
  • Yamada Y ; Abe R ; Okano Y ; Miyakawa Y
  • Intern Med 2017[]; 56 (9 ): 1085-1088 PMID28458317 show ga
  • We experienced a favorable outcome in an adult case of atypical hemolytic uremic syndrome (aHUS) after long-term eculizumab treatment. A 38-year-old Japanese man with a history of central retinal vein occlusion was admitted to our hospital with progressive dyspnea. He was found to have non-immune hemolytic anemia, thrombocytopenia, and acute renal failure two weeks after an episode of the common cold. Plasma exchange was ineffective; therefore, we initiated eculizumab after we excluded other thrombotic microangiopathies. Although long-term peritoneal dialysis was required, we successfully discontinued dialysis 18 months after the onset of aHUS with eculizumab.
  • |Adult [MESH]
  • |Antibodies, Monoclonal, Humanized/*therapeutic use [MESH]
  • |Asian People [MESH]
  • |Atypical Hemolytic Uremic Syndrome/diagnosis/*drug therapy [MESH]
  • |Humans [MESH]
  • |Kidney Failure, Chronic/*drug therapy/*etiology [MESH]
  • |Male [MESH]
  • |Thrombotic Microangiopathies/*diet therapy/*etiology [MESH]


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