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10.1155/2017/1789395 http://scihub22266oqcxt.onion/10.1155/2017/1789395 C5476901!5476901!28676863     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28676863&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Diabetes+Res 2017 ; 2017 (ä): ä Nephropedia Template TP {{tp|p=28676863|t=2017. Muscle Lipid Metabolism: Role of Lipid Droplets and Perilipins |pdf=|usr=}}{{28676863}} gab.com Text Muscle Lipid Metabolism: Role of Lipid Droplets and Perilipins JO: J Diabetes Res http://www.kidney.de/pget.php?&tw=1&pmid=28676863 #FOAvip Skeletal muscle is one of the main regulators of carbohydrate and lipid metabolism in our organism, and therefore, it is highly susceptible to changes in glucose and fatty acid (FA) availability. Skeletal muscle is an extremely complex tissue: its metabolic capacity depends on the type of fibers it is made up of and the level of stimulation it undergoes, such as acute or chronic contraction. Obesity is often associated with increased FA levels, which leads to the accumulation of toxic lipid intermediates, oxidative stress, and autophagy in skeletal fibers. This lipotoxicity is one of the most common causes of insulin resistance (IR). In this scenario, the ?isolation? of certain lipids in specific cell compartments, through the action of the specific lipid droplet, perilipin (PLIN) family of proteins, is conceived as a lifeguard compensatory strategy. In this review, we summarize the cellular mechanism underlying lipid mobilization and metabolism inside skeletal muscle, focusing on the function of lipid droplets, the PLIN family of proteins, and how these entities are modified in exercise, obesity, and IR conditions. Twit Text FOAVip Muscle Lipid Metabolism: Role of Lipid Droplets and Perilipins ????J Diabetes Res http://www.kidney.de/pget.php?&tw=1&pmid=28676863 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28676863 #FOAvip English Wikipedia <ref>{{Cite pmid|28676863}}</ref> Muscle Lipid Metabolism: Role of Lipid Droplets and Perilipins #MMPMID28676863 Morales PE; Bucarey JL; Espinosa A J Diabetes Res 2017[]; 2017 (ä): ä PMID28676863show ga Skeletal muscle is one of the main regulators of carbohydrate and lipid metabolism in our organism, and therefore, it is highly susceptible to changes in glucose and fatty acid (FA) availability. Skeletal muscle is an extremely complex tissue: its metabolic capacity depends on the type of fibers it is made up of and the level of stimulation it undergoes, such as acute or chronic contraction. Obesity is often associated with increased FA levels, which leads to the accumulation of toxic lipid intermediates, oxidative stress, and autophagy in skeletal fibers. This lipotoxicity is one of the most common causes of insulin resistance (IR). In this scenario, the ?isolation? of certain lipids in specific cell compartments, through the action of the specific lipid droplet, perilipin (PLIN) family of proteins, is conceived as a lifeguard compensatory strategy. In this review, we summarize the cellular mechanism underlying lipid mobilization and metabolism inside skeletal muscle, focusing on the function of lipid droplets, the PLIN family of proteins, and how these entities are modified in exercise, obesity, and IR conditions. äMuscle Lipid Metabolism: Role of Lipid Droplets and Perilipins (epmc).pdf DeepDyve Pubget Overpricing