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10.2147/IJN.S138081 http://scihub22266oqcxt.onion/10.2147/IJN.S138081 C5476632!5476632!28652740     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Nanomedicine 2017 ; 12 (ä): 4397-407 Nephropedia Template TP {{tp|p=28652740|t=2017. Optical coding of fusion genes using multicolor quantum dots for prostate cancer diagnosis |pdf=|usr=}}{{28652740}} gab.com Text Optical coding of fusion genes using multicolor quantum dots for prostate cancer diagnosis JO: Int J Nanomedicine http://www.kidney.de/pget.php?&tw=1&pmid=28652740 #FOAvip Recent studies have found that prostate cancer expresses abnormal genetic markers including multiple types of TMPRSS2?ERG fusion genes. The expression level of different TMPRSS2?ERG fusion genes is correlated to pathologic variables of aggressive prostate cancer and disease progression. State-of-the-art methods for detection of TMPRSS2?ERG fusion genes include reverse transcription polymerase chain reaction (RT-PCR) with a detection limit of 1 fmol at urinary condition. RT-PCR is time consuming, costly, and inapplicable for multiplexing. Ability to identify multiple fusion genes in a single sample has become important for diagnostic and clinical purposes. There is a need for a sensitive diagnostic test to detect multiple TMPRSS2?ERG fusion genes for an early diagnosis and prognosis of prostate cancer. Here, we propose to develop an assay for prostate cancer diagnosis using oligonucleotide-functionalized quantum dot and magnetic microparticle for optical detection of rearranged TMPRSS2?ERG fusion genes at a low concentration in urine. We found that our assay was able to identify three different types of fusion gene with a wide detection range and detection limit of 1 fmol (almost the same level of the RT-PCR result reported). Here, we show detection of multiple TMPRSS2?ERG fusion genes using color-coded oligonucleotides in cell lysate and urine. Twit Text FOAVip Optical coding of fusion genes using multicolor quantum dots for prostate cancer diagnosis ????Int J Nanomedicine http://www.kidney.de/pget.php?&tw=1&pmid=28652740 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28652740 #FOAvip English Wikipedia <ref>{{Cite pmid|28652740}}</ref> Optical coding of fusion genes using multicolor quantum dots for prostate cancer diagnosis #MMPMID28652740 Lee H; Kim C; Lee D; Park JH; Searson PC; Lee KH Int J Nanomedicine 2017[]; 12 (ä): 4397-407 PMID28652740show ga Recent studies have found that prostate cancer expresses abnormal genetic markers including multiple types of TMPRSS2?ERG fusion genes. The expression level of different TMPRSS2?ERG fusion genes is correlated to pathologic variables of aggressive prostate cancer and disease progression. State-of-the-art methods for detection of TMPRSS2?ERG fusion genes include reverse transcription polymerase chain reaction (RT-PCR) with a detection limit of 1 fmol at urinary condition. RT-PCR is time consuming, costly, and inapplicable for multiplexing. Ability to identify multiple fusion genes in a single sample has become important for diagnostic and clinical purposes. There is a need for a sensitive diagnostic test to detect multiple TMPRSS2?ERG fusion genes for an early diagnosis and prognosis of prostate cancer. Here, we propose to develop an assay for prostate cancer diagnosis using oligonucleotide-functionalized quantum dot and magnetic microparticle for optical detection of rearranged TMPRSS2?ERG fusion genes at a low concentration in urine. We found that our assay was able to identify three different types of fusion gene with a wide detection range and detection limit of 1 fmol (almost the same level of the RT-PCR result reported). Here, we show detection of multiple TMPRSS2?ERG fusion genes using color-coded oligonucleotides in cell lysate and urine. äOptical coding of fusion genes using multicolor quantum dots for prost(epmc).pdf DeepDyve Pubget Overpricing