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10.1177/2192568217694142

http://scihub22266oqcxt.onion/10.1177/2192568217694142
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C5476348!5476348!28660105
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suck abstract from ncbi


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pmid28660105      Global+Spine+J 2017 ; 7 (3): 230-8
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  • Significance of Vertebral Endplate Failure in Symptomatic Lumbar Disc Herniation #MMPMID28660105
  • Sahoo MM; Mahapatra SK; Kaur S; Sarangi J; Mohapatra M
  • Global Spine J 2017[May]; 7 (3): 230-8 PMID28660105show ga
  • Study Design:: Prospective cohort study. Objective:: Endplate lesions though have been implicated in the genesis of lumbar disc herniation (LDH), very little is known regarding their clinical course. Thus, the present study is aimed to investigate the incidence and types of endplate failure (EPF) in LDH and its correlation with the clinical symptoms and prognosis. Methods:: Clinical and magnetic resonance imaging (MRI) features of 66 patients with isolated single level LDH were studied. Three-dimensional fast spoiled gradient (3D FSPGR) MRI and computed tomography scans were used to identify the bony and cartilaginous EPF. Twenty-five patients were operated on and 41 patients were treated conservatively. Changes in the pain score, function and neurology were noted at 3, 6, 12, 24, and 36 weeks. Results:: Endplate lesions were observed in 64 patients (96.9%), including bony endplate failure (bony failure) in 47 patients (71.2%) and isolated cartilaginous endplate lesions in 17 patients (25.7%). Bony failure group had similar pain and functional scores but more severe neurological deficit at the initial evaluation. Clinical parameters improved in all groups, but the recovery was lesser in conservatively treated bony failure patients. Conclusion:: Endplate lesions are commonly associated with symptomatic LDH. Presence of bony failure can increase neurological deficit and reduce the chance of recovery with conservative management. The 3D FSPGR sequence of MRI can be successfully used for detection of the endplate lesions in the herniated disc.
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