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10.1002/hep.28948

http://scihub22266oqcxt.onion/10.1002/hep.28948
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C5476301!5476301!27859502
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suck abstract from ncbi


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pmid27859502      Hepatology 2017 ; 65 (3): 1039-43
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  • The Origin of Fibrogenic Myofibroblasts in Fibrotic Liver #MMPMID27859502
  • Kisseleva T
  • Hepatology 2017[Mar]; 65 (3): 1039-43 PMID27859502show ga
  • Liver fibrosis results from chronic liver injury of different etiologies. It is characterized by dysregulation of physiological remodeling, activation of myofibroblasts, and formation of a fibrous scar. Myofibroblasts develop contractile functions and secrete the extracellular matrix proteins that form this fibrous scar. Myofibroblasts are not present in the normal liver but activate and proliferate in response to injury and inflammation. This review summarizes the understanding and controversies on the contribution of cell populations to the myofibroblasts in liver fibrosis.
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