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10.1073/pnas.1702312114 http://scihub22266oqcxt.onion/10.1073/pnas.1702312114 C5474826!5474826!28559338     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 276.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28559338.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Proc+Natl+Acad+Sci+U+S+A 2017 ; 114 (24): E4734-43 Nephropedia Template TP {{tp|p=28559338|t=2017. Superresolution microscopy reveals the three-dimensional organization of meiotic chromosome axes in intact Caenorhabditis elegans tissue |pdf=|usr=}}{{28559338}} gab.com Text Superresolution microscopy reveals the three-dimensional organization of meiotic chromosome axes in intact Caenorhabditis elegans tissue JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28559338 #FOAvip Meiosis is the essential cell division process that generates haploid gametes from diploid precursor cells. It relies on a dramatic reorganization of chromosomes around a central axis, which establishes a platform for homologous pairing and its subsequent stabilization by the formation of a proteinaceous structure, the synaptonemal complex, and by physical linkages resulting from crossover recombination events. Despite their central role in regulating key meiotic events, little is known about the organization of the chromosome axes. Here, we use superresolution microscopy, combined with CRISPR/Cas9 genome editing, to build a three-dimensional model of the synapsed chromosome axis. Our data link axis structure to its functions in synapsis and regulation of partner choice during meiotic double-strand break repair. Twit Text FOAVip Superresolution microscopy reveals the three-dimensional organization of meiotic chromosome axes in intact Caenorhabditis elegans tissue ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28559338 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28559338 #FOAvip English Wikipedia <ref>{{Cite pmid|28559338}}</ref> Superresolution microscopy reveals the three-dimensional organization of meiotic chromosome axes in intact Caenorhabditis elegans tissue #MMPMID28559338 Köhler S; Wojcik M; Xu K; Dernburg AF Proc Natl Acad Sci U S A 2017[Jun]; 114 (24): E4734-43 PMID28559338show ga Meiosis is the essential cell division process that generates haploid gametes from diploid precursor cells. It relies on a dramatic reorganization of chromosomes around a central axis, which establishes a platform for homologous pairing and its subsequent stabilization by the formation of a proteinaceous structure, the synaptonemal complex, and by physical linkages resulting from crossover recombination events. Despite their central role in regulating key meiotic events, little is known about the organization of the chromosome axes. Here, we use superresolution microscopy, combined with CRISPR/Cas9 genome editing, to build a three-dimensional model of the synapsed chromosome axis. Our data link axis structure to its functions in synapsis and regulation of partner choice during meiotic double-strand break repair. äSuperresolution microscopy reveals the three-dimensional organization (epmc).pdf DeepDyve Pubget Overpricing