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10.1002/wrna.1413 http://scihub22266oqcxt.onion/10.1002/wrna.1413 C5474163!5474163!28130830     free     free     free       Wiley+Interdiscip+Rev+RNA 2017 ; 8 (4): ä Nephropedia Template TP {{tp|p=28130830|t=2017. RNA in extracellular vesicles |pdf=|usr=}}{{28130830}} gab.com Text RNA in extracellular vesicles JO: Wiley Interdiscip Rev RNA http://www.kidney.de/pget.php?&tw=1&pmid=28130830 #FOAvip Cells release a range of membrane-enclosed extracellular vesicles (EVs) into the environment. Among them, exosomes and microvesicles (collectively measuring 30-1000 nm in diameter) carry proteins, signaling lipids, and nucleic acids from donor cells to recipient cells, and thus have been proposed to serve as intercellular mediators of communication. EVs transport cellular materials in many physiologic processes, including differentiation, stem cell homeostasis, immune responses, and neuronal signaling. EVs are also increasingly recognized as having a direct role in pathological processes, notably cancer and neurodegeneration. Accordingly, EVs have been the focus of intense investigation as biomarkers of disease and prognostic indicators, and even therapeutic tools. Here, we review the classes of RNAs present in EVs, both coding RNAs (mRNAs) and noncoding RNAs (long noncoding RNAs, microRNAs, and circular RNAs). The rising attention to EV-resident RNAs as biomarkers stems from the fact that RNAs can be detected at extremely low quantities using a number of methods. To illustrate the interest in EV biology, we discuss EV RNAs in cancer and neurodegeneration, two major age-associated disease processes. Twit Text FOAVip RNA in extracellular vesicles ????Wiley Interdiscip Rev RNA http://www.kidney.de/pget.php?&tw=1&pmid=28130830 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28130830 #FOAvip English Wikipedia <ref>{{Cite pmid|28130830}}</ref> RNA in extracellular vesicles #MMPMID28130830 Kim KM; Abdelmohsen K; Mustapic M; Kapogiannis D; Gorospe M Wiley Interdiscip Rev RNA 2017[Jul]; 8 (4): ä PMID28130830show ga Cells release a range of membrane-enclosed extracellular vesicles (EVs) into the environment. Among them, exosomes and microvesicles (collectively measuring 30-1000 nm in diameter) carry proteins, signaling lipids, and nucleic acids from donor cells to recipient cells, and thus have been proposed to serve as intercellular mediators of communication. EVs transport cellular materials in many physiologic processes, including differentiation, stem cell homeostasis, immune responses, and neuronal signaling. EVs are also increasingly recognized as having a direct role in pathological processes, notably cancer and neurodegeneration. Accordingly, EVs have been the focus of intense investigation as biomarkers of disease and prognostic indicators, and even therapeutic tools. Here, we review the classes of RNAs present in EVs, both coding RNAs (mRNAs) and noncoding RNAs (long noncoding RNAs, microRNAs, and circular RNAs). The rising attention to EV-resident RNAs as biomarkers stems from the fact that RNAs can be detected at extremely low quantities using a number of methods. To illustrate the interest in EV biology, we discuss EV RNAs in cancer and neurodegeneration, two major age-associated disease processes. äRNA in extracellular vesicles (epmc).pdf DeepDyve Pubget Overpricing