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10.14814/phy2.13262 http://scihub22266oqcxt.onion/10.14814/phy2.13262 C5471429!5471429!28576851     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 269.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Physiol+Rep 2017 ; 5 (11): ä Nephropedia Template TP {{tp|p=28576851|t=2017. Urinary Tamm?Horsfall protein, albumin, vitamin D?binding protein, and retinol?binding protein as early biomarkers of chronic kidney disease in dogs |pdf=|usr=}}{{28576851}} gab.com Text Urinary Tamm Horsfall protein, albumin, vitamin D binding protein, and retinol binding protein as early biomarkers of chronic kidney disease in dogs JO: Physiol Rep http://www.kidney.de/pget.php?&tw=1&pmid=28576851 #FOAvip Proteinuria is a marker and mediator of chronic kidney disease (CKD). In clinical practice, the urinary protein?to?creatinine ratio (UP/C) is of limited usefulness, because it indicates only the magnitude of proteinuria and not the origin of the loss (glomerular or tubular). The complete assessment of proteinuria includes quantitative and qualitative evaluations, both of which are required in order to optimize the therapy. In addition to measuring the UP/C, we performed SDS?PAGE and western blotting to determine the expression of albumin, vitamin D?binding protein (VDBP), retinol?binding protein (RBP), and Tamm?Horsfall protein (THP) in urine samples of 49 dogs: healthy (control) dogs (n = 9); and dogs with CKD (n = 40), stratified by stage. In the dogs with stage 3 or 4 CKD, there was a predominance of tubular proteins. Neither VDBP nor RBP was observed in the urine of the control dogs. Among the dogs with stage 1 or 2 CKD, VDBP and RBP were detected in those without proteinuria or with borderline proteinuria. The expression of urinary albumin was significantly higher in the stage 4 group than in any other group (P ? 0.01). In the stage 4 group, urinary THP was either undetectable or lower than in the control group (P ? 0.01). In conclusion, urinary VDBP and RBP might act as early markers of kidney injury, and a decrease in urinary THP could be an indicator of CKD progression. Twit Text FOAVip Urinary Tamm Horsfall protein, albumin, vitamin D binding protein, and retinol binding protein as early biomarkers of chronic kidney disease in dogs ????Physiol Rep http://www.kidney.de/pget.php?&tw=1&pmid=28576851 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28576851 #FOAvip English Wikipedia <ref>{{Cite pmid|28576851}}</ref> Urinary Tamm?Horsfall protein, albumin, vitamin D?binding protein, and retinol?binding protein as early biomarkers of chronic kidney disease in dogs #MMPMID28576851 Chacar F; Kogika M; Sanches TR; Caragelasco D; Martorelli C; Rodrigues C; Capcha JMC; Chew D; Andrade L Physiol Rep 2017[Jun]; 5 (11): ä PMID28576851show ga Proteinuria is a marker and mediator of chronic kidney disease (CKD). In clinical practice, the urinary protein?to?creatinine ratio (UP/C) is of limited usefulness, because it indicates only the magnitude of proteinuria and not the origin of the loss (glomerular or tubular). The complete assessment of proteinuria includes quantitative and qualitative evaluations, both of which are required in order to optimize the therapy. In addition to measuring the UP/C, we performed SDS?PAGE and western blotting to determine the expression of albumin, vitamin D?binding protein (VDBP), retinol?binding protein (RBP), and Tamm?Horsfall protein (THP) in urine samples of 49 dogs: healthy (control) dogs (n = 9); and dogs with CKD (n = 40), stratified by stage. In the dogs with stage 3 or 4 CKD, there was a predominance of tubular proteins. Neither VDBP nor RBP was observed in the urine of the control dogs. Among the dogs with stage 1 or 2 CKD, VDBP and RBP were detected in those without proteinuria or with borderline proteinuria. The expression of urinary albumin was significantly higher in the stage 4 group than in any other group (P ? 0.01). In the stage 4 group, urinary THP was either undetectable or lower than in the control group (P ? 0.01). In conclusion, urinary VDBP and RBP might act as early markers of kidney injury, and a decrease in urinary THP could be an indicator of CKD progression. äUrinary Tamm?Horsfall protein, albumin, vitamin D?binding protein, and(epmc).pdf DeepDyve Pubget Overpricing