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10.1186/s12864-017-3839-7 http://scihub22266oqcxt.onion/10.1186/s12864-017-3839-7 C5470263!5470263!28610613     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Genomics 2017 ; 18 (ä): ä Nephropedia Template TP {{tp|p=28610613|t=2017. 100 million years of multigene family evolution: origin and evolution of the avian MHC class IIB |pdf=|usr=}}{{28610613}} gab.com Text 100 million years of multigene family evolution: origin and evolution of the avian MHC class IIB JO: BMC Genomics http://www.kidney.de/pget.php?&tw=1&pmid=28610613 #FOAvip Background: Gene duplication has led to a most remarkable adaptation involved in vertebrates? host-pathogen arms-race, the major histocompatibility complex (MHC). However, MHC duplication history is as yet poorly understood in non-mammalian vertebrates, including birds. Results: Here, we provide evidence for the evolution of two ancient avian MHC class IIB (MHCIIB) lineages by a duplication event prior to the radiation of all extant birds >100 million years ago, and document the role of concerted evolution in eroding the footprints of the avian MHCIIB duplication history. Conclusions: Our results suggest that eroded footprints of gene duplication histories may mimic birth-death evolution and that in the avian MHC the presence of the two lineages may have been masked by elevated rates of concerted evolution in several taxa. Through the presence of a range of intermediate evolutionary stages along the homogenizing process of concerted evolution, the avian MHCIIB provides a remarkable illustration of the erosion of multigene family duplication history. Electronic supplementary material: The online version of this article (doi:10.1186/s12864-017-3839-7) contains supplementary material, which is available to authorized users. Twit Text FOAVip 100 million years of multigene family evolution: origin and evolution of the avian MHC class IIB ????BMC Genomics http://www.kidney.de/pget.php?&tw=1&pmid=28610613 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28610613 #FOAvip English Wikipedia <ref>{{Cite pmid|28610613}}</ref> 100 million years of multigene family evolution: origin and evolution of the avian MHC class IIB #MMPMID28610613 Goebel J; Promerová M; Bonadonna F; McCoy KD; Serbielle C; Strandh M; Yannic G; Burri R; Fumagalli L BMC Genomics 2017[]; 18 (ä): ä PMID28610613show ga Background: Gene duplication has led to a most remarkable adaptation involved in vertebrates? host-pathogen arms-race, the major histocompatibility complex (MHC). However, MHC duplication history is as yet poorly understood in non-mammalian vertebrates, including birds. Results: Here, we provide evidence for the evolution of two ancient avian MHC class IIB (MHCIIB) lineages by a duplication event prior to the radiation of all extant birds >100 million years ago, and document the role of concerted evolution in eroding the footprints of the avian MHCIIB duplication history. Conclusions: Our results suggest that eroded footprints of gene duplication histories may mimic birth-death evolution and that in the avian MHC the presence of the two lineages may have been masked by elevated rates of concerted evolution in several taxa. Through the presence of a range of intermediate evolutionary stages along the homogenizing process of concerted evolution, the avian MHCIIB provides a remarkable illustration of the erosion of multigene family duplication history. Electronic supplementary material: The online version of this article (doi:10.1186/s12864-017-3839-7) contains supplementary material, which is available to authorized users. ä100 million years of multigene family evolution: origin and evolution (epmc).pdf DeepDyve Pubget Overpricing