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2017 ; 17
(1
): 75
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Sclerosing mesenteritis and mesenteric panniculitis - clinical experience and
radiological features
#MMPMID28610559
Nyberg L
; Björk J
; Björkdahl P
; Ekberg O
; Sjöberg K
; Vigren L
BMC Gastroenterol
2017[Jun]; 17
(1
): 75
PMID28610559
show ga
BACKGROUND: Sclerosing mesenteritis (SM) is sometimes used as an umbrella-term
for idiopathic inflammatory conditions in the mesentery. Mesenteric panniculitis
(MP) is a radiological finding and its relation to clinical SM is not fully
understood. The aims of this study were to determine whether any correlation
could be found between the radiological findings and the clinical disease course.
METHODS: Patients observed due to idiopathic inflammation of the mesentery were
identified. If SM could be verified histologically or MP radiologically, the
patients were included in this descriptive retro perspective study. RESULTS:
Typical radiological changes were observed in 27 patients. A majority (23/27) of
these patients had mild to moderate symptoms. This group with typical radiology
was labelled MP. Four patients were included due to histologically verified
disease but had uncharacteristic radiology involving multiple compartments of the
abdomen. All four had marked systemic inflammation, fever and fluctuating
radiologic findings. Three had severe disease with multiple hospitalisations and
complications but responded promptly to corticosteroids. This group was denoted
SM. CONCLUSIONS: We have identified two subgroups of patients; firstly, MP with
stable and characteristic radiologic changes and secondly SM with atypical
radiology and a more aggressive clinical course. We propose that the term SM
should be reserved for this latter condition.