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10.1177/2045893217704838

http://scihub22266oqcxt.onion/10.1177/2045893217704838
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C5467938!5467938!28597775
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suck abstract from ncbi


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pmid28597775      Pulm+Circ 2017 ; 7 (2): 465-75
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  • Dobutamine stress MRI in pulmonary hypertension: relationships between stress pulmonary artery relative area change, RV performance, and 10-year survival #MMPMID28597775
  • Blyth KG; Bellofiore A; Jayasekera G; Foster JE; Steedman T; Chesler NC; Peacock AJ
  • Pulm Circ 2017[Jun]; 7 (2): 465-75 PMID28597775show ga
  • In pulmonary hypertension (PH), right ventricular (RV) performance determines survival. Pulmonary artery (PA) stiffening is an important biomechanical event in PH and also predicts survival based on the PA relative area change (RAC) measured at rest using magnetic resonance imaging (MRI). In this exploratory study, we sought to generate novel hypotheses regarding the influence of stress RAC on PH prognosis and the interaction between PA stiffening, RV performance and survival. Fifteen PH patients underwent dobutamine stress-MRI (ds-MRI) and right heart catheterization. RACREST, RACSTRESS, and ?RAC (RAC STRESS ? RAC REST) were correlated against resting invasive hemodynamics and ds-MRI data regarding RV performance and RV-PA coupling efficiency (n?vv [RV stroke volume/RV end-systolic volume]). The impact of RAC, RV data, and n?vv on ten-year survival were determined using Kaplan?Meier analysis. PH patients with a low ?RAC (
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