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10.1038/ncomms15431 http://scihub22266oqcxt.onion/10.1038/ncomms15431 C5465322!5465322!28580937     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2017 ; 8 (ä): ä Nephropedia Template TP {{tp|p=28580937|t=2017. Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish |pdf=|usr=}}{{28580937}} gab.com Text Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=28580937 #FOAvip The spreading of mesenchymal-like cell layers is critical for embryo morphogenesis and tissue repair, yet we know little of this process in vivo. Here we take advantage of unique developmental features of the non-conventional annual killifish embryo to study the principles underlying tissue spreading in a simple cellular environment, devoid of patterning signals and major morphogenetic cell movements. Using in vivo experimentation and physical modelling we reveal that the extra-embryonic epithelial enveloping cell layer, thought mainly to provide protection to the embryo, directs cell migration and the spreading of embryonic tissue during early development. This function relies on the ability of embryonic cells to couple their autonomous random motility to non-autonomous signals arising from the expansion of the extra-embryonic epithelium, mediated by cell membrane adhesion and tension. Thus, we present a mechanism of extra-embryonic control of embryo morphogenesis that couples the mechanical properties of adjacent tissues in the early killifish embryo. Twit Text FOAVip Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=28580937 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28580937 #FOAvip English Wikipedia <ref>{{Cite pmid|28580937}}</ref> Extra-embryonic tissue spreading directs early embryo morphogenesis in killifish #MMPMID28580937 Reig G; Cerda M; Sepúlveda N; Flores D; Castañeda V; Tada M; Härtel S; Concha ML Nat Commun 2017[]; 8 (ä): ä PMID28580937show ga The spreading of mesenchymal-like cell layers is critical for embryo morphogenesis and tissue repair, yet we know little of this process in vivo. Here we take advantage of unique developmental features of the non-conventional annual killifish embryo to study the principles underlying tissue spreading in a simple cellular environment, devoid of patterning signals and major morphogenetic cell movements. Using in vivo experimentation and physical modelling we reveal that the extra-embryonic epithelial enveloping cell layer, thought mainly to provide protection to the embryo, directs cell migration and the spreading of embryonic tissue during early development. This function relies on the ability of embryonic cells to couple their autonomous random motility to non-autonomous signals arising from the expansion of the extra-embryonic epithelium, mediated by cell membrane adhesion and tension. Thus, we present a mechanism of extra-embryonic control of embryo morphogenesis that couples the mechanical properties of adjacent tissues in the early killifish embryo. äExtra-embryonic tissue spreading directs early embryo morphogenesis in(epmc).pdf DeepDyve Pubget Overpricing