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10.1038/s41598-017-03376-7 http://scihub22266oqcxt.onion/10.1038/s41598-017-03376-7 C5465189!5465189 !28596583     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 261.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28596583 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Sci+Rep 2017 ; 7 (1 ): 3117 Nephropedia Template TP {{tp|p=28596583 |t=2017. Dynamic Contrast-enhanced MRI in Renal Tumors: Common Subtype Differentiation using Pharmacokinetics |pdf=|usr=}}{{28596583 }} gab.com Text Dynamic Contrast-enhanced MRI in Renal Tumors: Common Subtype Differentiation using Pharmacokinetics JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28596583 #FOAvip Preoperative renal tumor subtype differentiation is important for radiology and urology in clinical practice. Pharmacokinetic data (K (trans) & V (e), etc.) derived from dynamic contrast-enhanced MRI (DCE-MRI) have been used to investigate tumor vessel permeability. In this prospective study on DCE-MRI pharmacokinetic studies, we enrolled patients with five common renal tumor subtypes: clear cell renal cell carcinoma (ccRCC; n?=?65), papillary renal cell carcinoma (pRCC; n?=?12), chromophobic renal cell carcinoma (cRCC; n?=?9), uroepithelial carcinoma (UEC; n?=?14), and fat-poor angiomyolipoma (fpAML; n?=?10). The results show that K (trans) of ccRCC, pRCC, cRCC, UEC and fpAML (0.459?±?0.190?min(-1), 0.206?±?0.127?min(-1), 0.311?±?0.111?min(-1), 0.235?±?0.116?min(-1), 0.511?±?0.159?min(-1), respectively) were different, but V (e) was not. K (trans) could distinguish ccRCC from non-ccRCC (pRCC & cRCC) with a sensitivity of 76.9% and a specificity of 71.4%, respectively, as well as to differentiate fpAML from non-ccRCC with a sensitivity of 100% and a specificity of 76.2%, respectively. Our findings suggest that DCE-MRI pharmacokinetics are promising for differential diagnosis of renal tumors, especially for RCC subtype characterization and differentiation between fpAML and non-ccRCC, which may facilitate the treatment of renal tumors. Twit Text FOAVip Dynamic Contrast-enhanced MRI in Renal Tumors: Common Subtype Differentiation using Pharmacokinetics ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28596583 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28596583 #FOAvip English Wikipedia <ref>{{Cite pmid|28596583 }}</ref> Dynamic Contrast-enhanced MRI in Renal Tumors: Common Subtype Differentiation using Pharmacokinetics #MMPMID28596583 Wang HY ; Su ZH ; Xu X ; Huang N ; Sun ZP ; Wang YW ; Li L ; Guo AT ; Chen X ; Ma X ; Ma L ; Ye HY Sci Rep 2017[Jun]; 7 (1 ): 3117 PMID28596583 show ga Preoperative renal tumor subtype differentiation is important for radiology and urology in clinical practice. Pharmacokinetic data (K (trans) & V (e), etc.) derived from dynamic contrast-enhanced MRI (DCE-MRI) have been used to investigate tumor vessel permeability. In this prospective study on DCE-MRI pharmacokinetic studies, we enrolled patients with five common renal tumor subtypes: clear cell renal cell carcinoma (ccRCC; n?=?65), papillary renal cell carcinoma (pRCC; n?=?12), chromophobic renal cell carcinoma (cRCC; n?=?9), uroepithelial carcinoma (UEC; n?=?14), and fat-poor angiomyolipoma (fpAML; n?=?10). The results show that K (trans) of ccRCC, pRCC, cRCC, UEC and fpAML (0.459?±?0.190?min(-1), 0.206?±?0.127?min(-1), 0.311?±?0.111?min(-1), 0.235?±?0.116?min(-1), 0.511?±?0.159?min(-1), respectively) were different, but V (e) was not. K (trans) could distinguish ccRCC from non-ccRCC (pRCC & cRCC) with a sensitivity of 76.9% and a specificity of 71.4%, respectively, as well as to differentiate fpAML from non-ccRCC with a sensitivity of 100% and a specificity of 76.2%, respectively. Our findings suggest that DCE-MRI pharmacokinetics are promising for differential diagnosis of renal tumors, especially for RCC subtype characterization and differentiation between fpAML and non-ccRCC, which may facilitate the treatment of renal tumors. |*Image Enhancement [MESH] |*Magnetic Resonance Imaging/methods [MESH] |Adult [MESH] |Antineoplastic Agents/pharmacokinetics/therapeutic use [MESH] |Cell Differentiation/drug effects [MESH] |Female [MESH] |Humans [MESH] |Kidney Neoplasms/*diagnostic imaging/drug therapy/metabolism/*pathology [MESH] |Male [MESH] |Middle Aged [MESH] |ROC Curve [MESH]Dynamic Contrast-enhanced MRI in Renal Tumors: Common Subtype Differen(epmc).pdf DeepDyve Pubget Overpricing