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10.1042/CS20170275

http://scihub22266oqcxt.onion/10.1042/CS20170275
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C5461940!5461940!28592701
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suck abstract from ncbi


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pmid28592701      Clin+Sci+(Lond) 2017 ; 131 (12): 1283-5
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  • Thrombospondin-1 contributes to slower aortic aneurysm growth by inhibiting maladaptive remodeling of extracellular matrix #MMPMID28592701
  • Satoh M; Nasu T; Osaki T; Hitomi S
  • Clin Sci (Lond) 2017[Jun]; 131 (12): 1283-5 PMID28592701show ga
  • In this issue of Clinical Science, Krishna and colleagues describe recent work on thrombospondin-1 (TSP-1) maturation and its association with slower growth of aortic aneurysm in TSP-1 knockdown mouse models. The authors conclude that TSP-1 deficiency promotes maladaptive remodeling of the extracellular matrix (ECM) leading to accelerated aortic aneurysm progression. We comment on a causal relation between TSP-1 and the progression of aortic aneurysm.
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