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10.3389/fcell.2017.00061 http://scihub22266oqcxt.onion/10.3389/fcell.2017.00061 C5461346!5461346!28638821     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Cell+Dev+Biol 2017 ; 5 (ä): ä Nephropedia Template TP {{tp|p=28638821|t=2017. The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth |pdf=|usr=}}{{28638821}} gab.com Text The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth JO: Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=28638821 #FOAvip Cell size is amenable by genetic and environmental factors. The highly conserved nutrient-responsive Target of Rapamycin (TOR) signaling pathway regulates cellular metabolic status and growth in response to numerous inputs. Timing and duration of TOR pathway activity is pivotal for both cell mass built up as well as cell cycle progression and is controlled and fine-tuned by the abundance and quality of nutrients, hormonal signals, growth factors, stress, and oxygen. TOR kinases function within two functionally and structurally discrete multiprotein complexes, TORC1 and TORC2, that are implicated in temporal and spatial control of cell size and growth respectively; however, recent data indicate that such functional distinctions are much more complex. Here, we briefly review roles of the two complexes in cellular growth and cytoarchitecture in various experimental model systems. Twit Text FOAVip The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth ????Front Cell Dev Biol http://www.kidney.de/pget.php?&tw=1&pmid=28638821 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28638821 #FOAvip English Wikipedia <ref>{{Cite pmid|28638821}}</ref> The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth #MMPMID28638821 Gonzalez S; Rallis C Front Cell Dev Biol 2017[]; 5 (ä): ä PMID28638821show ga Cell size is amenable by genetic and environmental factors. The highly conserved nutrient-responsive Target of Rapamycin (TOR) signaling pathway regulates cellular metabolic status and growth in response to numerous inputs. Timing and duration of TOR pathway activity is pivotal for both cell mass built up as well as cell cycle progression and is controlled and fine-tuned by the abundance and quality of nutrients, hormonal signals, growth factors, stress, and oxygen. TOR kinases function within two functionally and structurally discrete multiprotein complexes, TORC1 and TORC2, that are implicated in temporal and spatial control of cell size and growth respectively; however, recent data indicate that such functional distinctions are much more complex. Here, we briefly review roles of the two complexes in cellular growth and cytoarchitecture in various experimental model systems. äThe TOR Signaling Pathway in Spatial and Temporal Control of Cell Size(epmc).pdf DeepDyve Pubget Overpricing