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2017 ; 9
(7
): 560-566
Nephropedia Template TP
gab.com Text
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English Wikipedia
Variables to Predict Nephrological Disease in General, and Glomerulonephritis in
Particular, in Patients With Microhematuria
#MMPMID28611855
Bramlage CP
; Wallbach M
; Ellenberger D
; Deutsch C
; Minguet J
; Smith KH
; Stock J
; Goninski A
; Bramlage P
; Koziolek M
; Mueller GA
J Clin Med Res
2017[Jul]; 9
(7
): 560-566
PMID28611855
show ga
BACKGROUND: Microhematuria (MH) is a symptom frequently leading to uncertainty as
to when a nephrology referral is appropriate. Because MH may be indicative of
severe kidney disorders, prompt diagnosis and potential treatment initiation can
be important. We aimed to identify further variables that point at a
nephrological cause, in particular of glomerulonephritis (GN), when MH is
diagnosed. METHODS: A retrospective analysis of data acquired from patients
attending a nephrology office due to MH was performed. Demographic information
and diagnostic tests were evaluated in order to identify factors that were
associated with a nephrological cause. RESULTS: Patients with MH (n = 805) as
indicated by a urine stick analysis were included. Of these, MH was confirmed by
urine sediment analysis in 543 patients (67.5%). Of those, 48.3% had a
nephrological cause, including 12.4% with GN and 2.9% with rapid progressive GN
(RPGN). A urine dipstick finding of ? 250 erythrocytes per microliter,
microalbuminuria and elevated leukocytes increased the probability of having a GN
to 62.4%. Furthermore, the presence of microalbuminuria, GFR < 60 mL/min, history
of hypertension and diabetes mellitus increased the probability for all
nephrological causes to 95.4%. CONCLUSION: There are a number of factors
available that help to assess the need for a nephrology referral in patients with
microhematuria.