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2016 ; 9
(11
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Do Dental Resin Composites Accumulate More Oral Biofilms and Plaque than Amalgam
and Glass Ionomer Materials?
#MMPMID28774007
Zhang N
; Melo MAS
; Weir MD
; Reynolds MA
; Bai Y
; Xu HHK
Materials (Basel)
2016[Nov]; 9
(11
): ä PMID28774007
show ga
A long-time drawback of dental composites is that they accumulate more biofilms
and plaques than amalgam and glass ionomer restorative materials. It would be
highly desirable to develop a new composite with reduced biofilm growth, while
avoiding the non-esthetics of amalgam and low strength of glass ionomer. The
objectives of this study were to: (1) develop a protein-repellent composite with
reduced biofilms matching amalgam and glass ionomer for the first time; and (2)
investigate their protein adsorption, biofilms, and mechanical properties. Five
materials were tested: A new composite containing 3% of protein-repellent
2-methacryloyloxyethyl phosphorylcholine (MPC); the composite with 0% MPC as
control; commercial composite control; dental amalgam; resin-modified glass
ionomer (RMGI). A dental plaque microcosm biofilm model with human saliva as
inoculum was used to investigate metabolic activity, colony-forming units (CFU),
and lactic acid production. Composite with 3% MPC had flexural strength similar
to those with 0% MPC and commercial composite control (p > 0.1), and much greater
than RMGI (p < 0.05). Composite with 3% MPC had protein adsorption that was only
1/10 that of control composites (p < 0.05). Composite with 3% MPC had biofilm CFU
and lactic acid much lower than control composites (p < 0.05). Biofilm growth,
metabolic activity and lactic acid on the new composite with 3% MPC were reduced
to the low level of amalgam and RMGI (p > 0.1). In conclusion, a new
protein-repellent dental resin composite reduced oral biofilm growth and acid
production to the low levels of non-esthetic amalgam and RMGI for the first time.
The long-held conclusion that dental composites accumulate more biofilms than
amalgam and glass ionomer is no longer true. The novel composite is promising to
finally overcome the major biofilm-accumulation drawback of dental composites in
order to reduce biofilm acids and secondary caries.