Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1165/rcmb.2013-0397TR http://scihub22266oqcxt.onion/10.1165/rcmb.2013-0397TR C5455301!5455301!24219511     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Respir+Cell+Mol+Biol 2014 ; 50 (4): 667-77 Nephropedia Template TP {{tp|p=24219511|t=2014. Targeting Insulin-Like Growth Factor-I and Insulin-Like Growth Factor?Binding Protein-3 Signaling Pathways A Novel Therapeutic Approach for Asthma |pdf=|usr=}}{{24219511}} gab.com Text Targeting Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Protein-3 Signaling Pathways A Novel Therapeutic Approach for Asthma JO: Am J Respir Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=24219511 #FOAvip Insulin-like growth factor (IGF)-I has been recognized to play critical roles in the pathogenesis of asthma, whereas IGF-binding protein (IGFBP)-3 blocks crucial physiologic manifestations of asthma. IGF-I enhances subepithelial fibrosis, airway inflammation, airway hyperresponsiveness, and airway smooth muscle hyperplasia by interacting with various inflammatory mediators and complex signaling pathways, such as intercellular adhesion molecule-1, and the hypoxia-inducible factor/vascular endothelial growth factor axis. On the other hand, IGFBP-3 decreases airway inflammation and airway hyperresponsiveness through IGFBP-3 receptor?mediated activation of caspases, which subsequently inhibits NF-?B signaling pathway. It also inhibits the IGF-I/hypoxia-inducible factor/vascular endothelial growth factor axis via IGF-I?dependent and/or IGF-I?independent mechanisms. This Translational Review summarizes the role of IGF-I and IGFBP-3 in the context of allergic airway disease, and discusses the therapeutic potential of various strategies targeting the IGF-I and IGFBP-3 signaling pathways for the management of asthma. Twit Text FOAVip Targeting Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Protein-3 Signaling Pathways A Novel Therapeutic Approach for Asthma ????Am J Respir Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=24219511 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24219511 #FOAvip English Wikipedia <ref>{{Cite pmid|24219511}}</ref> Targeting Insulin-Like Growth Factor-I and Insulin-Like Growth Factor?Binding Protein-3 Signaling Pathways A Novel Therapeutic Approach for Asthma #MMPMID24219511 Lee H; Kim SR; Oh Y; Cho SH; Schleimer RP; Lee YC Am J Respir Cell Mol Biol 2014[Apr]; 50 (4): 667-77 PMID24219511show ga Insulin-like growth factor (IGF)-I has been recognized to play critical roles in the pathogenesis of asthma, whereas IGF-binding protein (IGFBP)-3 blocks crucial physiologic manifestations of asthma. IGF-I enhances subepithelial fibrosis, airway inflammation, airway hyperresponsiveness, and airway smooth muscle hyperplasia by interacting with various inflammatory mediators and complex signaling pathways, such as intercellular adhesion molecule-1, and the hypoxia-inducible factor/vascular endothelial growth factor axis. On the other hand, IGFBP-3 decreases airway inflammation and airway hyperresponsiveness through IGFBP-3 receptor?mediated activation of caspases, which subsequently inhibits NF-?B signaling pathway. It also inhibits the IGF-I/hypoxia-inducible factor/vascular endothelial growth factor axis via IGF-I?dependent and/or IGF-I?independent mechanisms. This Translational Review summarizes the role of IGF-I and IGFBP-3 in the context of allergic airway disease, and discusses the therapeutic potential of various strategies targeting the IGF-I and IGFBP-3 signaling pathways for the management of asthma. äTargeting Insulin-Like Growth Factor-I and Insulin-Like Growth Factor?(epmc).pdf DeepDyve Pubget Overpricing