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10.1093/ckj/sfw147

http://scihub22266oqcxt.onion/10.1093/ckj/sfw147
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C5455215!5455215!28584627
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suck abstract from ncbi


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pmid28584627      Clin+Kidney+J 2017 ; 10 (2): 266-8
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  • Mixed leukocyte cell-derived chemotaxin 2 and amyloid A renal amyloidosis in a Kazakh-German patient #MMPMID28584627
  • Gödecke VA; Röcken C; Steinmüller-Magin L; Nadrowitz F; Fleig SV; Haller H; Wagner AD
  • Clin Kidney J 2017[Apr]; 10 (2): 266-8 PMID28584627show ga
  • Leukocyte cell-derived chemotaxin 2 (LECT2)-related amyloidosis (ALECT2) constitutes a subtype of systemic amyloidosis affecting the kidney. This is the first case describing mixed ALECT2 and Amyloid A renal amyloidosis in a Kazakh-German patient. Genetic analysis shows a polymorphism in the LECT2 gene and a homozygous mutation in the SAA1 gene. Notably, our patient has a body mass index of 61?kg/m2 and a pathological glucose tolerance test. ALECT2 was found in certain ethnic groups with a high incidence of diabetes. In our case, morbid obesity may have played a significant role in clinical manifestation of ALECT2 amyloidosis.
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