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10.1097/TP.0000000000001582 http://scihub22266oqcxt.onion/10.1097/TP.0000000000001582 C5453852!5453852!27906824     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Transplantation 2017 ; 101 (7): 1551-8 Nephropedia Template TP {{tp|p=27906824|t=2017. SELECTION OF PATIENTS FOR INITIAL CLINICAL TRIALS OF SOLID ORGAN XENOTRANSPLANTATION |pdf=|usr=}}{{27906824}} gab.com Text SELECTION OF PATIENTS FOR INITIAL CLINICAL TRIALS OF SOLID ORGAN XENOTRANSPLANTATION JO: Transplantation http://www.kidney.de/pget.php?&tw=1&pmid=27906824 #FOAvip Several groups have reported extended survival of genetically-engineered pig organs in nonhuman primates, varying from almost 10 months for life-supporting kidney grafts and >2 years for nonlife-supporting heart grafts to less than 1 month for life-supporting liver and lung grafts. We have attempted to define groups of patients who may not have an option to wait for an allograft. These include kidney, heart, and lung candidates who are highly-allosensitized. In addition, some kidney candidates (who have previously lost at least 2 allografts from rapid recurrence of native kidney disease) have a high risk of further recurrence and will not be offered a repeat allotransplant. Patients with complex congenital heart disease, who may have undergone previous palliative surgical procedures, may be unsuitable for ventricular assist device implantation. Patients dying of fulminant hepatic failure, for whom no alternative therapy is available, may be candidates for a pig liver, even if only as a bridge until an allograft becomes available. When the results of pig organ xenotransplantation in nonhuman primates suggest a realistic potential for success of a pilot clinical trial, highly-selected patients should be offered participation. Twit Text FOAVip SELECTION OF PATIENTS FOR INITIAL CLINICAL TRIALS OF SOLID ORGAN XENOTRANSPLANTATION ????Transplantation http://www.kidney.de/pget.php?&tw=1&pmid=27906824 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27906824 #FOAvip English Wikipedia <ref>{{Cite pmid|27906824}}</ref> SELECTION OF PATIENTS FOR INITIAL CLINICAL TRIALS OF SOLID ORGAN XENOTRANSPLANTATION #MMPMID27906824 Cooper DK; Wijkstrom M; Hariharan S; Chan JL; Singh A; Horvath K; Mohiuddin M; Cimeno A; Barth RN; LaMattina JC; Pierson RN Transplantation 2017[Jul]; 101 (7): 1551-8 PMID27906824show ga Several groups have reported extended survival of genetically-engineered pig organs in nonhuman primates, varying from almost 10 months for life-supporting kidney grafts and >2 years for nonlife-supporting heart grafts to less than 1 month for life-supporting liver and lung grafts. We have attempted to define groups of patients who may not have an option to wait for an allograft. These include kidney, heart, and lung candidates who are highly-allosensitized. In addition, some kidney candidates (who have previously lost at least 2 allografts from rapid recurrence of native kidney disease) have a high risk of further recurrence and will not be offered a repeat allotransplant. Patients with complex congenital heart disease, who may have undergone previous palliative surgical procedures, may be unsuitable for ventricular assist device implantation. Patients dying of fulminant hepatic failure, for whom no alternative therapy is available, may be candidates for a pig liver, even if only as a bridge until an allograft becomes available. When the results of pig organ xenotransplantation in nonhuman primates suggest a realistic potential for success of a pilot clinical trial, highly-selected patients should be offered participation. äSELECTION OF PATIENTS FOR INITIAL CLINICAL TRIALS OF SOLID ORGAN XENOT(epmc).pdf DeepDyve Pubget Overpricing