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10.1152/ajpheart.00680.2016

http://scihub22266oqcxt.onion/10.1152/ajpheart.00680.2016
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C5451582!5451582!28213406
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suck abstract from ncbi


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pmid28213406      Am+J+Physiol+Heart+Circ+Physiol 2017 ; 312 (5): H1096-104
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  • Mitochondria-regulated formation of endothelium-derived extracellular vesicles shifts the mediator of flow-induced vasodilation #MMPMID28213406
  • Freed JK; Durand MJ; Hoffmann BR; Densmore JC; Greene AS; Gutterman DD
  • Am J Physiol Heart Circ Physiol 2017[May]; 312 (5): H1096-104 PMID28213406show ga
  • The vascular effect of endothelium-derived extracellular vesicles (eEVs) is biphasic, with higher doses decreasing the magnitude of flow-induced dilation (FID) compared with lower doses that shift the mediator of FID from nitric oxide to H2O2. eEVs may cause vascular dysfunction via similar pathways despite being formed from different stimuli, although both require mitochondrial reactive oxygen species for their formation.
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