Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1098/rsob.170077 http://scihub22266oqcxt.onion/10.1098/rsob.170077 C5451548!5451548 !28566301     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28566301 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Open+Biol 2017 ; 7 (5 ): ä Nephropedia Template TP {{tp|p=28566301 |t=2017. Understanding RNA modifications: the promises and technological bottlenecks of the epitranscriptome |pdf=|usr=}}{{28566301 }} gab.com Text Understanding RNA modifications: the promises and technological bottlenecks of the epitranscriptome JO: Open Biol http://www.kidney.de/pget.php?&tw=1&pmid=28566301 #FOAvip The discovery of mechanisms that alter genetic information via RNA editing or introducing covalent RNA modifications points towards a complexity in gene expression that challenges long-standing concepts. Understanding the biology of RNA modifications represents one of the next frontiers in molecular biology. To this date, over 130 different RNA modifications have been identified, and improved mass spectrometry approaches are still adding to this list. However, only recently has it been possible to map selected RNA modifications at single-nucleotide resolution, which has created a number of exciting hypotheses about the biological function of RNA modifications, culminating in the proposition of the 'epitranscriptome'. Here, we review some of the technological advances in this rapidly developing field, identify the conceptual challenges and discuss approaches that are needed to rigorously test the biological function of specific RNA modifications. Twit Text FOAVip Understanding RNA modifications: the promises and technological bottlenecks of the epitranscriptome ????Open Biol http://www.kidney.de/pget.php?&tw=1&pmid=28566301 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28566301 #FOAvip English Wikipedia <ref>{{Cite pmid|28566301 }}</ref> Understanding RNA modifications: the promises and technological bottlenecks of the epitranscriptome #MMPMID28566301 Schaefer M ; Kapoor U ; Jantsch MF Open Biol 2017[May]; 7 (5 ): ä PMID28566301 show ga The discovery of mechanisms that alter genetic information via RNA editing or introducing covalent RNA modifications points towards a complexity in gene expression that challenges long-standing concepts. Understanding the biology of RNA modifications represents one of the next frontiers in molecular biology. To this date, over 130 different RNA modifications have been identified, and improved mass spectrometry approaches are still adding to this list. However, only recently has it been possible to map selected RNA modifications at single-nucleotide resolution, which has created a number of exciting hypotheses about the biological function of RNA modifications, culminating in the proposition of the 'epitranscriptome'. Here, we review some of the technological advances in this rapidly developing field, identify the conceptual challenges and discuss approaches that are needed to rigorously test the biological function of specific RNA modifications. |*Epigenesis, Genetic [MESH] |*RNA Editing [MESH] |Animals [MESH] |Epigenomics/*methods [MESH] |Gene Expression Profiling/*methods [MESH] |High-Throughput Nucleotide Sequencing/methods [MESH] |Humans [MESH] |Molecular Biology/methods/trends [MESH]Understanding RNA modifications: the promises and technological bottle(epmc).pdf DeepDyve Pubget Overpricing