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10.1116/1.4984008 http://scihub22266oqcxt.onion/10.1116/1.4984008 C5451317!5451317!28565914     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biointerphases 2017 ; 12 (2): ä Nephropedia Template TP {{tp|p=28565914|t=2017. Human melanoma inhibitory protein binds to the FN12-14 Hep II domain of fibronectin |pdf=|usr=}}{{28565914}} gab.com Text Human melanoma inhibitory protein binds to the FN12-14 Hep II domain of fibronectin JO: Biointerphases http://www.kidney.de/pget.php?&tw=1&pmid=28565914 #FOAvip The heparin binding site (Hep II) of fibronectin plays a major role in tumor cell metastasis. Its interaction with heparan sulfate proteoglycans occurs in a variety of physiological processes including focal adhesion and migration. The melanoma inhibitory activity (MIA) is an important protein that is functionally involved in melanoma development, progression, and tumor cell invasion. After its secretion by malignant melanoma cells, MIA interacts with fibronectin and thereby actively facilitates focal cell detachment from surrounding structures and strongly promotes tumor cell invasion and the formation of metastases. In this report, the authors have determined the molecular basis of the interaction of MIA with the Hep II domain of fibronectin based on nuclear magnetic resonance spectroscopic binding assays. The authors have identified the type III modules 12 to 14 of fibronectin's Hep II as the major MIA binding sites. These results now provide a new target protein?protein binding interface for the discovery of novel antimetastatic agents against malignant melanoma in the future. Twit Text FOAVip Human melanoma inhibitory protein binds to the FN12-14 Hep II domain of fibronectin ????Biointerphases http://www.kidney.de/pget.php?&tw=1&pmid=28565914 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28565914 #FOAvip English Wikipedia <ref>{{Cite pmid|28565914}}</ref> Human melanoma inhibitory protein binds to the FN12-14 Hep II domain of fibronectin #MMPMID28565914 Yip KT; Zhong X; Seibel N; Arnolds O; Schöpel M; Stoll R Biointerphases 2017[Jun]; 12 (2): ä PMID28565914show ga The heparin binding site (Hep II) of fibronectin plays a major role in tumor cell metastasis. Its interaction with heparan sulfate proteoglycans occurs in a variety of physiological processes including focal adhesion and migration. The melanoma inhibitory activity (MIA) is an important protein that is functionally involved in melanoma development, progression, and tumor cell invasion. After its secretion by malignant melanoma cells, MIA interacts with fibronectin and thereby actively facilitates focal cell detachment from surrounding structures and strongly promotes tumor cell invasion and the formation of metastases. In this report, the authors have determined the molecular basis of the interaction of MIA with the Hep II domain of fibronectin based on nuclear magnetic resonance spectroscopic binding assays. The authors have identified the type III modules 12 to 14 of fibronectin's Hep II as the major MIA binding sites. These results now provide a new target protein?protein binding interface for the discovery of novel antimetastatic agents against malignant melanoma in the future. äHuman melanoma inhibitory protein binds to the FN12-14 Hep II domain o(epmc).pdf DeepDyve Pubget Overpricing