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10.3389/fphar.2017.00304 http://scihub22266oqcxt.onion/10.3389/fphar.2017.00304 C5450331!5450331!28620298     free     free     free       Front+Pharmacol 2017 ; 8 (ä): ä Nephropedia Template TP {{tp|p=28620298|t=2017. Anti-tumor Activity of Toll-Like Receptor 7 Agonists |pdf=|usr=}}{{28620298}} gab.com Text Anti-tumor Activity of Toll-Like Receptor 7 Agonists JO: Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=28620298 #FOAvip Toll-like receptors (TLRs) are a class of pattern recognition receptors that play a bridging role in innate immunity and adaptive immunity. The activated TLRs not only induce inflammatory responses, but also elicit the development of antigen specific immunity. TLR7, a member of TLR family, is an intracellular receptor expressed on the membrane of endosomes. TLR7 can be triggered not only by ssRNA during viral infections, but also by immune modifiers that share a similar structure to nucleosides. Its powerful immune stimulatory action can be potentially used in the anti-tumor therapy. This article reviewed the anti-tumor activity and mechanism of TLR7 agonists that are frequently applied in preclinical and clinical investigations, and mainly focused on small synthetic molecules, including imiquimod, resiquimod, gardiquimod, and 852A, etc. Twit Text FOAVip Anti-tumor Activity of Toll-Like Receptor 7 Agonists ????Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=28620298 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28620298 #FOAvip English Wikipedia <ref>{{Cite pmid|28620298}}</ref> Anti-tumor Activity of Toll-Like Receptor 7 Agonists #MMPMID28620298 Chi H; Li C; Zhao FS; Zhang L; Ng TB; Jin G; Sha O Front Pharmacol 2017[]; 8 (ä): ä PMID28620298show ga Toll-like receptors (TLRs) are a class of pattern recognition receptors that play a bridging role in innate immunity and adaptive immunity. The activated TLRs not only induce inflammatory responses, but also elicit the development of antigen specific immunity. TLR7, a member of TLR family, is an intracellular receptor expressed on the membrane of endosomes. TLR7 can be triggered not only by ssRNA during viral infections, but also by immune modifiers that share a similar structure to nucleosides. Its powerful immune stimulatory action can be potentially used in the anti-tumor therapy. This article reviewed the anti-tumor activity and mechanism of TLR7 agonists that are frequently applied in preclinical and clinical investigations, and mainly focused on small synthetic molecules, including imiquimod, resiquimod, gardiquimod, and 852A, etc. äAnti-tumor Activity of Toll-Like Receptor 7 Agonists (epmc).pdf DeepDyve Pubget Overpricing