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10.1165/rcmb.2016-0307TR http://scihub22266oqcxt.onion/10.1165/rcmb.2016-0307TR C5449515!5449515!27854509     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Respir+Cell+Mol+Biol 2017 ; 56 (4): 432-42 Nephropedia Template TP {{tp|p=27854509|t=2017. Transforming Growth Factor ?1 Function in Airway Remodeling and Hyperresponsiveness The Missing Link?|pdf=|usr=}}{{27854509}} gab.com Text Transforming Growth Factor 1 Function in Airway Remodeling and Hyperresponsiveness The Missing Link JO: Am J Respir Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=27854509 #FOAvip The pathogenesis of asthma includes a complex interplay among airway inflammation, hyperresponsiveness, and remodeling. Current evidence suggests that airway structural cells, including bronchial smooth muscle cells, myofibroblasts, fibroblasts, and epithelial cells, mediate all three aspects of asthma pathogenesis. Although studies show a connection between airway remodeling and changes in bronchomotor tone, the relationship between the two remains unclear. Transforming growth factor ?1 (TGF-?1), a growth factor elevated in the airway of patients with asthma, plays a role in airway remodeling and in the shortening of various airway structural cells. However, the role of TGF-?1 in mediating airway hyperresponsiveness remains unclear. In this review, we summarize the literature addressing the role of TGF-?1 in airway remodeling and shortening. Through our review, we aim to further elucidate the role of TGF-?1 in asthma pathogenesis and the link between airway remodeling and airway hyperresponsiveness in asthma and to define TGF-?1 as a potential therapeutic target for reducing asthma morbidity and mortality. Twit Text FOAVip Transforming Growth Factor 1 Function in Airway Remodeling and Hyperresponsiveness The Missing Link ????Am J Respir Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=27854509 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27854509 #FOAvip English Wikipedia <ref>{{Cite pmid|27854509}}</ref> Transforming Growth Factor ?1 Function in Airway Remodeling and Hyperresponsiveness The Missing Link? #MMPMID27854509 Ojiaku CA; Yoo EJ; Panettieri RA Am J Respir Cell Mol Biol 2017[Apr]; 56 (4): 432-42 PMID27854509show ga The pathogenesis of asthma includes a complex interplay among airway inflammation, hyperresponsiveness, and remodeling. Current evidence suggests that airway structural cells, including bronchial smooth muscle cells, myofibroblasts, fibroblasts, and epithelial cells, mediate all three aspects of asthma pathogenesis. Although studies show a connection between airway remodeling and changes in bronchomotor tone, the relationship between the two remains unclear. Transforming growth factor ?1 (TGF-?1), a growth factor elevated in the airway of patients with asthma, plays a role in airway remodeling and in the shortening of various airway structural cells. However, the role of TGF-?1 in mediating airway hyperresponsiveness remains unclear. In this review, we summarize the literature addressing the role of TGF-?1 in airway remodeling and shortening. Through our review, we aim to further elucidate the role of TGF-?1 in asthma pathogenesis and the link between airway remodeling and airway hyperresponsiveness in asthma and to define TGF-?1 as a potential therapeutic target for reducing asthma morbidity and mortality. äTransforming Growth Factor ?1 Function in Airway Remodeling and Hyperr(epmc).pdf DeepDyve Pubget Overpricing